Evidence map›Paper›PMID 27668333›Full record

ReviewCanadian journal of surgery. Journal canadien de chirurgie2016

Post-breast surgery pain syndrome: establishing a consensus for the definition of post-mastectomy pain syndrome to provide a standardized clinical and research approach - a review of the literature and discussion.

Daniel Waltho, Gloria Rockwell

3 registry-linked trialsAbstract readReview
In one paragraph

Review in Canadian journal of surgery. Journal canadien de chirurgie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03586154 phase4completednot on this mapstarted 2017, after this paper: background citation

Combined Platelet Rich Plasma Intra-articular Shoulder Injection and Stellate Ganglion Block. A New Technique for Management of Chronic Post-mastectomy Shoulder Pain Syndrome

TypeinterventionalSponsorMansoura UniversityRan2017 to 2018Enrolled70ConditionsBreast NeoplasmsArmsPlatelet rich plasma, ketamine and bupivacaine injection
NCT05458154 nacompletednot on this mapstarted 2021, after this paper: background citation

Evaluation and Re-evaluation of Post-mastectomy Pain Syndrome by Breast Cancer EDGE Task Force Outcomes: Clinical Measures of Pain After Pain Management Protocol of Physiotherapy

TypeinterventionalSponsorGeneral Committee of Teaching Hospitals and Institutes, EgyptRan2021 to 2022Enrolled10ConditionsPost-mastectomy Pain SyndromeArmsquestionnaires
NCT06036979 naunknown statusnot on this mapstarted 2024, after this paper: background citation

A Comparative Study Between Preoperative Erector Spinae Plane Block Versus Preoperative Paravertebral Plane Block in Decreasing Post Mastectomy Pain Syndrome. A Randomized Controlled Study.

TypeinterventionalSponsorNational Cancer Institute, EgyptRan2024 to 2025Enrolled51ConditionsChronic Postoperative PainArmsParavertebral plane block, Erector spinae plane block, Intravenous morphine, ketorlac and paracetamol
3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Trial
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  4. "This is the first time I felt they're mine": the significance of tattoos in coping and identity reconstruction following mastectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  10. Addressing the Needs of Breast Cancer Survivors.Current oncology reports · 2025
    Review
  11. Article
  12. Article
  13. Long-term health-related quality of life among adolescent and young adult breast cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  14. Review
  15. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel WalthoFrom the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Waltho); and the Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Rockwell).
Gloria RockwellFrom the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Waltho); and the Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Rockwell).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-mastectomy pain syndrome (PMPS) is a frequent complication of breast surgery. There is currently no standard definition for this chronic pain syndrome. The purpose of this review was to establish a consensus for defining PMPS by identifying the various elements included in the definitions and how they vary across the literature, determining how these definitions affect the methodological components therein, and proposing a definition that appropriately encompasses all of the appropriate elements.

methodsWe searched PubMed to retrieve all studies and case reports on PMPS, and we analyzed definitions of PMPS, inclusion/exclusion criteria, and methods of measuring PMPS.

resultsTwenty-three studies were included in this review. We identified 7 independent domains for defining PMPS: surgical breast procedure, neuropathic nature, pain of at least moderate intensity, protracted duration, frequent symptoms, appropriate location of the symptoms and exacerbation with movement. These domains were used with varying frequency. Inclusion/exclusion criteria and methods for assessing PMPS also varied markedly.

conclusionTo prevent future discrepancies in both the clinical and research settings, we propose a new and complete definition based on the results of our review: PMPS is pain that occurs after any breast surgery; is of at least moderate severity; possesses neuropathic qualities; is located in the ipsilateral breast/chest wall, axilla, and/or arm; lasts at least 6 months; occurs at least 50% of the time; and may be exacerbated by movements of the shoulder girdle.

Indexed as

ConsensusHumansMastectomyPostoperative Pain

Identifiers

PMID27668333
PMCPMC5042722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.