ArticleAnnals of translational medicine2016
Effectiveness of enteral feeding protocol on clinical outcomes in critically ill patients: a study protocol for before-and-after design.
Article in Annals of translational medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial.Critical care (London, England) · 2022Trial
- Clinical field survey and multidisciplinary expert in-depth interview study on food for special medical purpose products for patients.Clinical nutrition research · 2026Article
- Gastrointestinal complications in intensive care.Medical review (2021) · 2025Review
- [The clinical impact of implementation of a nutritional treatment protocol in critically ill adults with SARS-CoV-2 infection].Revista espanola de anestesiologia y reanimacion · 2023Article
- Article
- Factors Associated with Interruptions of Enteral Nutrition and the Impact on Macro- and Micronutrient Deficits in ICU Patients.Nutrients · 2023Article
- Effect of early enteral nutrition on critical care outcomes in patients with acute ischemic stroke.The Journal of international medical research · 2021Observational
- Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals.Critical care (London, England) · 2018Article
- Instrumental variable analysis in the presence of unmeasured confounding.Annals of translational medicine · 2018Article
- Effect of team training on efficiency of trauma care in a Chinese hospital.The Journal of international medical research · 2018Article
- Studying the effect of abdominal massage on the gastric residual volume in patients hospitalized in intensive care units.Journal of intensive care · 2018Article
- Impact and outcomes of nutritional support team intervention in patients with gastrointestinal disease in the intensive care unit.Medicine · 2017Article
- Management of a patient with Opalski's syndrome in intensive care unit.Clinical case reports · 2017Article
- Effectiveness of enteral feeding protocol on clinical outcomes in critically ill patients: A before and after study.PloS one · 2017Article
- How should this patient with repeated aspiration pneumonia be managed and treated?-a proposal of the Percutaneous ENdoscopIc Gastrostomy and Tracheostomy (PENlIGhT) procedure.Journal of thoracic disease · 2016Review
Corrections and comments
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Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEnteral feed is an important component of nutritional therapy in critically ill patients and underfeeding has been associated with adverse outcomes. The article developed an enteral feeding protocol and planed a before-and-after comparative trial to explore whether implementation of enteral feeding protocol was able to improve clinical outcomes. METHODS AND ANALYSIS: The study will be conducted in intensive care units (ICUs) of ten tertiary care academic centers. Critically ill patients expected to stay in ICU for over 3 days and require enteral nutrition (EN) were potentially eligible. This is a before-and-after study comprising three phases: The first phase is the period without enteral feeding protocol; the second phase involves four-week training program, and the last phase is to perform the protocol in participating centers. We plan to enroll a total of 350 patients to provide an 80% power and 0.05 error rate to detect a 15% reduction of mortality. The primary outcome is 28-day mortality. ETHICS AND DISSEMINATION: Ethical approval to conduct the research has been obtained from all participating centers. Additionally, the results will be published in peer-reviewed journal.
trial registrationThe study was registered at International Standard Registered Clinical/soCial sTudy Number (ISRCTN) registry (ISRCTN10583582).
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