ArticleObstetrics & gynecology science2016
Primary malignant melanoma of cervix and vagina.
Article in Obstetrics & gynecology science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Advances in the diagnosis and treatment of primary malignant melanoma of the vagina- a case presentation and systematic review.BMC women's health · 2025Pooled it
- Cutaneous Malignancies Metastatic to the Female Genital Tract and Pelvic Lymph Nodes: Analysis of Metastatic Patterns and Pathogenesis.Journal of clinical medicine · 2026Review
- Primary cervical malignant melanoma that was successfully treated with pembrolizumab: a case report and literature review.Frontiers in oncology · 2024Article
- Primary Melanoma of the Cervix Uteri: A Systematic Review and Meta-Analysis of the Reported Cases.Biology · 2023Review
- Genitourinary melanoma: An overview for the clinician.Asian journal of urology · 2022Review
- Primary Malignant Melanoma of the Cervix: An Integrated Analysis of Case Reports and Series.Frontiers in oncology · 2022Article
- Management of a primary malignant melanoma of uterine cervix stage IVA patient with radical surgery and adjuvant oncolytic virus RigvirClinical case reports · 2020Article
- Primary Malignant Melanoma of the Cervix: A Case Report and a Review of the Literature.Case reports in oncological medicine · 2020Article
- Primary malignant melanomas of the female lower genital tract: clinicopathological characteristics and management.American journal of cancer research · 2020Review
- Predictive biomarkers and tumor microenvironment in female genital melanomas: a multi-institutional study of 55 cases.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary malignant melanoma (MM) accounts for 1% of all cancers, and only 3% to 7% of these tumors occur in the female genital tract. Data are limited with respect to the basis for treatment recommendations because of the rarity of MM. The overall prognosis of melanomas of the female genital tract is very poor. Two cases of MM of the female genital tract are presented. The first case is of a 70-year-old female patient who complained of left thigh pain and underwent magnetic resonance imaging that showed cervical cancer with involvement of the vagina, bladder, and parametrium, in addition to multiple bony metastases of the proximal femur, acetabulum, and both iliac bones. The second case is of a 35-year-old female patient who suffered from vaginal bleeding for 5 months, and she was diagnosed as having primary vaginal melanoma. The patient underwent radical surgery and two additional surgeries because of recurrence of cancer in both inguinal areas. After surgery, the patient received adjuvant immunotherapy, radiation therapy, and chemotherapy. In both the aforementioned cases, the pathologic diagnosis was made after immunohistochemical analysis, i.e., the tumor cells were stained with HMB-45 and S100, and were found to be positive for both immunostains.
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Registered trials
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