Evidence map›Paper›PMID 27668095›Full record

ArticleCase reports in anesthesiology2016

Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation.

A L M J van der Knijff-van Dortmont, M Dirckx, J J Duvekot, J W Roos-Hesselink, A Gonzalez Candel, C D van der Marel, G P Scoones, V F R Adriaens, I J J Dons-Sinke

Open access · goldAbstract read
In one paragraph

Article in Case reports in anesthesiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

A L M J van der Knijff-van DortmontDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.ORCID 0000-0002-9994-7602
M DirckxDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.ORCID 0000-0002-4306-654X
J J DuvekotDepartment of Obstetrics and Gynaecology, Erasmus University Medical Centre, Rotterdam, Netherlands.
J W Roos-HesselinkDepartment of Cardiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
A Gonzalez CandelDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
C D van der MarelDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
G P ScoonesDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.ORCID 0000-0002-6460-1994
V F R AdriaensDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.
I J J Dons-SinkeDepartment of Anesthesiology, Erasmus University Medical Centre, Rotterdam, Netherlands.ORCID 0000-0001-9233-6385
Erasmus University Rotterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SCN5A gene mutations can lead to ion channel defects which can cause cardiac conduction disturbances. In the presence of specific ECG characteristics, this mutation is called Brugada syndrome. Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging. In this case report, we describe a pregnant patient with this mutation who received epidural analgesia using low dose ropivacaine and sufentanil during labour.

Identifiers

PMID27668095
PMCPMC5030394
OpenAlexW2508646796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.