ArticleSocial psychiatry and psychiatric epidemiology2016
Global patterns of workplace productivity for people with depression: absenteeism and presenteeism costs across eight diverse countries.
Article in Social psychiatry and psychiatric epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04234776 (Intramuscular Ketamine Versus Escitalopram and Aripiprazole in Acute and Maintenance Treatment of Patients With Treatment-resistant Depression), which is not on this map. Cited by 162 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intramuscular Ketamine Versus Escitalopram and Aripiprazole in Acute and Maintenance Treatment of Patients With Treatment-resistant Depression
Who cites it
162 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Occupational health interventions' impact on absenteeism and economic returns: A systematic review and meta-analysis.Scandinavian journal of work, environment & health · 2026Pooled it
- Performance of Automatic Speech Analysis in Detecting Depression: Systematic Review and Meta-Analysis.JMIR mental health · 2025Pooled it
- Change in Cognitive Function over the Course of Major Depressive Disorder: A Systematic Review and Meta-analysis.Neuropsychology review · 2025Pooled it
- Universal, selective and indicated interventions for supporting mental health at the workplace: an umbrella review of meta-analyses.Occupational and environmental medicine · 2023Pooled it
- Interventions to improve return to work in depressed people.The Cochrane database of systematic reviews · 2020Pooled it
- Predicting Absenteeism and Temporary Disability Using Machine Learning: a Systematic Review and Analysis.Journal of medical systems · 2020Pooled it
- Effects of smartphone cognitive behavioural therapy on social functioning in non-depressive and subthreshold depressive adults: a secondary analysis of the RESiLIENT trial.BMJ mental health · 2026Trial
- Testing the Pragmatic Effectiveness of a Consumer-Based Mindfulness Mobile App in the Workplace: Randomized Controlled Trial.JMIR mHealth and uHealth · 2022Trial
- Trial
- A Single-Day Training for Managers Reduces Cognitive Stigma Regarding Mental Health Problems: A Randomized Trial.International journal of environmental research and public health · 2022Trial
- Psychometric assessment of EQ-5D-5L and ReQoL measures in patients with anxiety and depression: construct validity and responsiveness.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Trial
- The relationship between depression risk perception and self-help behaviours in high risk Canadians: a cross-sectional study.BMC public health · 2020Trial
- Randomized, double-blind, placebo-controlled study to assess the efficacy and safety of vortioxetine in Japanese patients with major depressive disorder.Psychiatry and clinical neurosciences · 2020Trial
- Trial
- Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial.Arthritis care & research · 2018Trial
- Trial
- Development of MHFA-based 2-h educational program for early intervention in depression among office workers: A single-arm pilot trial.PloS one · 2018Trial
- The consequences of changes in exercise habits on work engagement and presenteeism: Evidence from an event-study analysis using Japanese longitudinal data.Scandinavian journal of work, environment & health · 2026Article
- Global economic burden of depression in 154 countries from 2025 to 2050.Nature medicine · 2026Article
- Perceptions of Change in Depression Among Participants in a Program Based on Permission Theory.Healthcare (Basel, Switzerland) · 2026Article
102 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDepression is a leading cause of disability worldwide. Research suggests that by far, the greatest contributor to the overall economic impact of depression is loss in productivity; however, there is very little research on the costs of depression outside of Western high-income countries. Thus, this study examines the impact of depression on workplace productivity across eight diverse countries.
methodsWe estimated the extent and costs of depression-related absenteeism and presenteeism in the workplace across eight countries: Brazil, Canada, China, Japan, South Korea, Mexico, South Africa, and the USA. We also examined the individual, workplace, and societal factors associated with lower productivity.
resultsTo the best of our knowledge, this is the first study to examine the impact of depression on workplace productivity across a diverse set of countries, in terms of both culture and GDP. Mean annual per person costs for absenteeism were lowest in South Korea at $181 and highest in Japan ($2674). Mean presenteeism costs per person were highest in the USA ($5524) and Brazil ($5788). Costs associated with presenteeism tended to be 5-10 times higher than those associated with absenteeism.
conclusionsThese findings suggest that the impact of depression in the workplace is considerable across all countries, both in absolute monetary terms and in relation to proportion of country GDP. Overall, depression is an issue deserving much greater attention, regardless of a country's economic development, national income or culture.
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