Evidence map›Paper›PMID 27667131›Full record

ArticleGenome biology and evolution2016

TRT, a Vertebrate and Protozoan Tc1-Like Transposon: Current Activity and Horizontal Transfer.

Hua-Hao Zhang, Guo-Yin Li, Xiao-Min Xiong, Min-Jin Han, Xiao-Gu Zhang, Fang-Yin Dai

Open access · goldAbstract read
In one paragraph

Article in Genome biology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hua-Hao ZhangState Key Laboratory of Silkworm Genome Biology, Key Laboratory for Sericulture Functional Genomics and Biotechnology of Agricultural Ministry, Southwest University, Chongqing, China College of Pharmacy and Life Science, Jiujiang University, Jiujiang, China.
Guo-Yin LiDepartment of pathology, Hanzhoung Hospital, Hanzhoung city, Shaanxi, China.
Xiao-Min XiongClinical Medical College, Jiujiang University, Jiujiang, China.
Min-Jin HanState Key Laboratory of Silkworm Genome Biology, Key Laboratory for Sericulture Functional Genomics and Biotechnology of Agricultural Ministry, Southwest University, Chongqing, China.
Xiao-Gu ZhangCollege of Pharmacy and Life Science, Jiujiang University, Jiujiang, China.
Fang-Yin DaiState Key Laboratory of Silkworm Genome Biology, Key Laboratory for Sericulture Functional Genomics and Biotechnology of Agricultural Ministry, Southwest University, Chongqing, China fydai@swu.edu.cn.
Jiujiang University · CNSouthwest University · CNState Key Laboratory of Silkworm Genomic Biology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a Danio rerio transposon named DrTRT, for D. rerio Transposon Related to Tc1 The complete sequence of the DrTRT transposon is 1,563 base pairs (bp) in length, and its transposase putatively encodes a 338-amino acid protein that harbors a DD37E motif in its catalytic domain. We present evidence based on searches of publicly available genomes that TRT elements commonly occur in vertebrates and protozoa. Phylogenetic and functional domain comparisons confirm that TRT constitutes a new subfamily within the Tc1 family. Hallmark features of having no premature termination codons within the transposase, the presence of all expected functional domains, and its occurrence in the bony fish transcriptome suggest that TRT might have current or recent activity in these species. Further analysis showed that the activity of TRT elements in these species might have arisen about between 4 and 19 Ma. Interestingly, our results also implied that the widespread distribution of TRT among fishes, frog, and snakes is the result of multiple independent HT events, probably from bony fishes to snakes or frog. Finally, the mechanisms underlying horizontal transfer of TRT elements are discussed.

Indexed as

DNA Transposable ElementsGene Transfer, HorizontalAmino Acid MotifsAnimalsCatalytic DomainCodon, TerminatorDNA-Binding ProteinsPhylogenyProtozoan ProteinsTransposasesZebrafishZebrafish ProteinsCodon, TerminatorDNA-Binding ProteinsDNA Transposable Elementsmariner transposasesProtozoan ProteinsTransposasesZebrafish ProteinsDD37Ehorizontal transferTc1/mariner transposons

Identifiers

PMID27667131
PMCPMC5630946
OpenAlexW2522423540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.