ArticleScientific reports2016
Novel highly divergent reassortant bat rotaviruses in Cameroon, without evidence of zoonosis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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Who cites it
32 citing papers in PubMed, 56 citations in OpenAlex.
- Identification of a putative novel rotavirus A VP4 genotype in bats from an urban Atlantic Forest, in the metropolitan region of Rio de Janeiro State, Southeastern Brazil.Archives of virology · 2026Article
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- Novel 20th century rotavirus alphagastroenteritidis strains identified in formalin-fixed and ethanol-preserved museum specimens.Molecular biology and evolution · 2026Article
- First molecular detection of five gastroenteritis viruses in untreated wastewater and impact of seasonal change on their distribution in Cameroon.One health (Amsterdam, Netherlands) · 2025Article
- Serological and molecular analysis of henipavirus infections in synanthropic fruit bat and rodent populations in the Centre and North regions of Cameroon (2018-2020).BMC veterinary research · 2025Article
- Isolation and Characterization of Distinct Rotavirus A in Bat and Rodent Hosts.Journal of virology · 2023Article
- Novel Virus Identification through Metagenomics: A Systematic Review.Life (Basel, Switzerland) · 2022Review
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- Virome of Bat-Infesting Arthropods: Highly Divergent Viruses in Different Vectors.Journal of virology · 2022Article
- High Prevalence of Coinfecting Enteropathogens in Suspected Rotavirus Vaccine Breakthrough Cases.Journal of clinical microbiology · 2021Article
- Hidden Viral Sequences in Public Sequencing Data and Warning for Future Emerging Diseases.mBio · 2021Article
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- Characterizing and Evaluating the Zoonotic Potential of Novel Viruses Discovered in Vampire Bats.Viruses · 2021Article
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- Comparative genomic analysis of genogroup 1 and genogroup 2 rotaviruses circulating in seven US cities, 2014-2016.Virus evolution · 2021Article
- Novel viruses detected in bats in the Republic of Korea.Scientific reports · 2020Article
- Epidemiology and Molecular Characterization of Rotavirus A in Fruit Bats in Bangladesh.EcoHealth · 2020Article
- An Extensive Meta-Metagenomic Search Identifies SARS-CoV-2-Homologous Sequences in Pangolin Lung Viromes.mSphere · 2020Article
- Article
- Viruses in bats and potential spillover to animals and humans.Current opinion in virology · 2019Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bats are an important reservoir for zoonotic viruses. To date, only three RVA strains have been reported in bats in Kenya and China. In the current study we investigated the genetic diversity of RVAs in fecal samples from 87 straw-colored fruit bats living in close contact with humans in Cameroon using viral metagenomics. Five (near) complete RVA genomes were obtained. A single RVA strain showed a partial relationship with the Kenyan bat RVA strain, whereas the other strains were completely novel. Only the VP7 and VP4 genes showed significant variability, indicating the occurrence of frequent reassortment events. Comparing these bat RVA strains with currently used human RVA screening primers indicated that most of the novel VP7 and VP4 segments would not be detected in routine epidemiological screening studies. Therefore, novel consensus screening primers were developed and used to screen samples from infants with gastroenteritis living in close proximity with the studied bat population. Although RVA infections were identified in 36% of the infants, there was no evidence of zoonosis. This study identified multiple novel bat RVA strains, but further epidemiological studies in humans will have to assess if these viruses have the potential to cause gastroenteritis in humans.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.