Evidence map›Paper›PMID 27666290›Full record

ArticleScientific reports2016

Multi-functional nano silver: A novel disruptive and theranostic agent for pathogenic organisms in real-time.

Ponnusamy Manogaran Gopinath, Anandan Ranjani, Dharumadurai Dhanasekaran, Nooruddin Thajuddin, Govindaraju Archunan, Mohammad Abdulkader Akbarsha, Balázs Gulyás, Parasuraman Padmanabhan

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Opportunities for Nanomedicine inAntibiotics (Basel, Switzerland) · 2021
    Review
  4. Biosynthesis of Silver Nanoparticles Using Culture Supernatant ofInternational journal of nanomedicine · 2020
    Article
  5. Applications of Noble Metal-Based Nanoparticles in Medicine.International journal of molecular sciences · 2018
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ponnusamy Manogaran GopinathDepartment of Microbiology, Bharathidasan University, Tiruchirappalli-620 024, India.
Anandan RanjaniDepartment of Microbiology, Bharathidasan University, Tiruchirappalli-620 024, India.
Dharumadurai DhanasekaranDepartment of Microbiology, Bharathidasan University, Tiruchirappalli-620 024, India.
Nooruddin ThajuddinDepartment of Microbiology, Bharathidasan University, Tiruchirappalli-620 024, India.
Govindaraju ArchunanNational Centre for Alternatives to Animal Experiments (NCAAE), Bharathidasan University, Tiruchirappalli-620 024, India.
Mohammad Abdulkader AkbarshaNational Centre for Alternatives to Animal Experiments (NCAAE), Bharathidasan University, Tiruchirappalli-620 024, India.
Balázs GulyásLee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.
Parasuraman PadmanabhanLee Kong Chian School of Medicine, Nanyang Technological University, 636921, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was aimed at evaluating the fluorescence property, sporicidal potency against Bacillus and Clostridium endospores, and surface disinfecting ability of biogenic nano silver. The nano silver was synthesized using an actinobacterial cell-filtrate. The fluorescence property as well as imaging facilitator potency of this nano silver was verified adopting spectrofluorometer along with fluorescent and confocal laser scanning microscope wherein strong emission and bright green fluorescence, respectively, on the entire spore surface was observed. Subsequently, the endospores of B. subtilis, B. cereus, B. amyloliquefaciens, C. perfringens and C. difficile were treated with physical sporicides, chemical sporicides and nano silver, in which the nano silver brought about pronounced inhibition even at a very low concentration. Finally, the environmental surface-sanitizing potency of nano silver was investigated adopting cage co-contamination assay, wherein vital organs of mice exposed to the nano silver-treated cage did not show any signs of pathological lesions, thus signifying the ability of nano silver to completely disinfect the spore or reduce the count required for infection. Taken these observations together, we have shown the multi-functional biological properties of the nano silver, synthesized using an actinobacterial cell-filtrate, which could be of application in advanced diagnostics, biomedical engineering and therapeutics in the near future.

Identifiers

PMID27666290
PMCPMC5036090

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.