Observational studyResuscitation2017
Association between chest compression rates and clinical outcomes following in-hospital cardiac arrest at an academic tertiary hospital.
Observational study in Resuscitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 3. Adult basic life support.Clinical and experimental emergency medicine · 2026Guideline
- The effect of chest compression frequency on the quality of resuscitation by lifeguards. A prospective randomized crossover multicenter simulation trial.Cardiology journal · 2019Trial
- Addition of Audiovisual Feedback During Standard Compressions Is Associated with Improved Ability.The western journal of emergency medicine · 2018Trial
- Article
- Left rib fractures during cardiopulmonary resuscitation are associated with hemodynamic variations in a pig model of cardiac arrest.Resuscitation plus · 2023Article
- Effect of the Brief Instructional Video Intervention on the Quality of Cardiopulmonary Resuscitation.International journal of medical sciences · 2023Article
- Readiness of Bystander Cardiopulmonary Resuscitation (BCPR) during the COVID-19 Pandemic: A Review.International journal of environmental research and public health · 2022Review
- Evaluation of the quality of cardiopulmonary resuscitation provided by the emergency response team at a tertiary care hospital.Indian journal of anaesthesia · 2022Article
- Innovative Tele-Instruction Approach Impacts Basic Life Support Performance: A Non-inferiority Trial.Frontiers in medicine · 2022Article
- Extracorporeal cardiopulmonary resuscitation in adults and children: A review of literature, published guidelines and pediatric single-center program building experience.Frontiers in medicine · 2022Review
- [Basic life support].Notfall & rettungsmedizin · 2021Review
- Efficacy of a Simplified Feedback Trainer for High-Quality Chest Compression Training: A Randomized Controlled Simulation Study.Frontiers in public health · 2021Article
- Quality of Cardiopulmonary Resuscitation and 5-Year Survival Following in-Hospital Cardiac Arrest.Open access emergency medicine : OAEM · 2021Article
- Adult Basic Life Support: International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.Resuscitation · 2020Article
- Data-driven classification of arrest location for emergency department cardiac arrests.Resuscitation · 2020Article
- Validating peer-led assessments of CPR performance.Resuscitation plus · 2020Article
- Article
- Ventilation rate and successful recovery from cardiac arrest: illusory correlation bias or real effect?Internal and emergency medicine · 2020Article
- Effects of Chest Compression Fraction on Return of Spontaneous Circulation in Patients with Cardiac Arrest; a Brief Report.Advanced journal of emergency medicine · 2020Article
- Feasibility of an augmented reality cardiopulmonary resuscitation training system for health care providers.Heliyon · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
aimsRecent guidelines for management of cardiac arrest recommend chest compression rates of 100-120 compressions/min. However, animal studies have found cardiac output to increase with rates up to 150 compressions/min. The objective of this study was to test the association between chest compression rates during cardiopulmonary resuscitation for in-hospital cardiac arrest (IHCA) and outcome.
methodsWe conducted a prospective observational study at a single academic medical center. INCLUSION CRITERIA: age≥18, IHCA, cardiopulmonary resuscitation performed. We analyzed chest compression rates measured by defibrillation electrodes, which recorded changes in thoracic impedance. The primary outcome was return of spontaneous circulation (ROSC). We used multivariable logistic regression to determine odds ratios for ROSC by chest compression rate categories (100-120, 121-140, >140 compressions/min), adjusted for chest compression fraction (proportion of time chest compressions provided) and other known predictors of outcome. We set 100-120 compressions/min as the reference category for the multivariable model.
resultsWe enrolled 222 consecutive patients and found a mean chest compression rate of 139±15. Overall 53% achieved ROSC; among 100-120, 121-140, and >140 compressions/min, ROSC was 29%, 64%, and 49% respectively. A chest compression rate of 121-140 compressions/min had the greatest likelihood of ROSC, odds ratio 4.48 (95% CI 1.42-14.14).
conclusionsIn this sample of adult IHCA patients, a chest compression rate of 121-140 compressions/min had the highest odds ratio of ROSC. Rates above the currently recommended 100-120 compressions/min may improve the chances of ROSC among IHCA patients.
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