Evidence map›Paper›PMID 27665146›Full record

ArticleDental materials : official publication of the Academy of Dental Materials2016

Influence of nanogel additive hydrophilicity on dental adhesive mechanical performance and dentin bonding.

Valeria B Gotti, Américo B Correr, Steven H Lewis, Victor P Feitosa, Lourenço Correr-Sobrinho, Jeffrey W Stansbury

Open access · greenAbstract read
In one paragraph

Article in Dental materials : official publication of the Academy of Dental Materials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Evolution of Dental Resin Adhesives-A Comprehensive Review.Journal of functional biomaterials · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Valeria B GottiDepartment of Restorative Dentistry, Division of Dental Materials, Piracicaba Dental School, State University of Campinas, 901 Limeira Ave., 13414-903 Piracicaba, Brazil. Electronic address: val_bisinoto@hotmail.com.
Américo B CorrerDepartment of Restorative Dentistry, Division of Dental Materials, Piracicaba Dental School, State University of Campinas, 901 Limeira Ave., 13414-903 Piracicaba, Brazil. Electronic address: amerbc@yahoo.com.br.
Steven H LewisDepartment of Craniofacial Biology, University of Colorado-School of Dental Medicine, 12800 E 19th Ave./RC1-North-Rm. 2104, Mail Stop 8310, Aurora, United States. Electronic address: steven.lewis@ucdenver.edu.
Victor P FeitosaDepartment of Restorative Dentistry, Dental School, Federal University of Ceará, Monsenhor Furtado St., 60430350 Fortaleza, Brazil. Electronic address: victorpfeitosa@hotmail.com.
Lourenço Correr-SobrinhoDepartment of Restorative Dentistry, Division of Dental Materials, Piracicaba Dental School, State University of Campinas, 901 Limeira Ave., 13414-903 Piracicaba, Brazil. Electronic address: sobrinho@fop.unicamp.br.
Jeffrey W StansburyDepartment of Craniofacial Biology, University of Colorado-School of Dental Medicine, 12800 E 19th Ave./RC1-North-Rm. 2104, Mail Stop 8310, Aurora, United States. Electronic address: jeffrey.stansbury@ucdenver.edu.
Universidade Estadual de Campinas (UNICAMP) · BRUniversity of Colorado Denver · USUniversidade Federal do Ceará · BR

Funding

Monomers and nanogel to improve adhesive resin structural integrity/durabilityR01DE023197 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI STANSBURY, JEFFREY W. · 2013 to 2017
$1.8M
NIDCR NIH HHS R01 DE023197
6 · The paper itself

Abstract

objectiveTo assess the influence of hydrophilicity of reactive nanogels on the mechanical performance of dental adhesives and microtensile bond strength (μTBS) to dentin after 24h or 3 months of aging.

methodsA series of three nanogels were synthesized: NG1-IBMA/UDMA; NG2-HEMA/BisGMA; NG3-HEMA/TE-EGDMA. The nanogels were dispersed in solvent, HEMA or BisGMA/HEMA. The degree of conversion (DC) of the materials was measured and the flexural modulus of these polymers was evaluated in dry or wet conditions. For μTBS analysis, a model adhesive was used without nanogel (control) or with the incorporation of nanogels. μTBS was evaluated after storage in distilled water for 24h or 3 months. The analysis of the fracture was performed after μTBS testing. Data were analyzed using ANOVA and Tukey's test (α=0.05).

resultsWater significantly increased the modulus of NG1 and NG2 dispersed in solvent, while significantly decreased the stiffness of NG3. All polymers dispersed in HEMA and BisGMA/HEMA had significantly lower modulus when stored in water. NG2 showed the highest DC in solvent and BisGMA/HEMA. In HEMA, NG1 and NG3 produced the highest DC. After three months, NG2 showed the best μTBS. The μTBS of NG2-containing adhesive resin significantly increased after 3 months, while storage had no effect in the control group, NG1 and NG3. SIGNIFICANCE: The more hydrophobic IBMA/UDMA nanogel showed higher bulk material mechanical property results, but the best dentin bond strength values, and notably strength values that improved upon storage, were obtained with the amphiphilic nanogel based on BisGMA/HEMA.

Indexed as

Dental CementsDentin-Bonding AgentsNanocompositesComposite ResinsDental BondingDentinHydrophobic and Hydrophilic InteractionsMethacrylatesResin CementsStress, MechanicalTensile StrengthComposite ResinsDental CementsDentin-Bonding AgentsMethacrylatesResin CementsAdhesionDental materialHydrolysisHydrophilicityNanogel

Identifiers

PMID27665146
PMCPMC5506551
OpenAlexW2522801567

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.