Evidence map›Paper›PMID 27664979›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2017

Determinants of longitudinal health-related quality-of-life change in children with asthma from low-income families: a report from the PROMIS

Z Li, W L Leite, L A Thompson, H E Gross, E A Shenkman, B B Reeve, D A DeWalt, I-C Huang

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04566835 (The Evaluation of Education With Cartoon's Effectiveness on Disease Management of the Children With Asthma), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04566835 nacompletednot on this mapstarted 2019, after this paper: background citation

The Evaluation of Education With Cartoon's Effectiveness on Disease Management of the Children With Asthma

TypeinterventionalSponsorBahçeşehir UniversityRan2019 to 2020Enrolled74ConditionsAsthma in ChildrenArmsStandart Care given during normal examination, Health Promotion Program with cartoon education for Children with Asthma
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Longitudinal validation of the PROMIS-16 in a sample of adults in the United States with back pain.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Z LiCollege of Nursing and Health Professions, Valparaiso University, Valparaiso, IN, USA.
W L LeiteSchool of Human Development and Organizational Studies in Education, College of Education, University of Florida, Gainesville, FL, USA.
L A ThompsonDepartment of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA.
H E GrossCecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
E A ShenkmanDepartment of Health Outcomes and Policy, College of Medicine, University of Florida, Gainesville, FL, USA.
B B ReeveCecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
D A DeWaltCecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
I-C HuangDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
University of Florida · USUniversity of North Carolina at Chapel Hill · USSt. Jude Children's Research Hospital · USValparaiso University · US

Funding

PROMIS Pediatrics: Longitudinal Validation and Linking Pediatric and Adult Item BU01AR052181 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI REEVE, BRYCE B · 2004 to 2013
$9.1M
NIAMS NIH HHS U01 AR052181
6 · The paper itself

Abstract

backgroundHow the longitudinal asthma control status and other socio-demographic factors influence the changes of health-related quality of life (HRQOL) among asthmatic children, especially from low-income families, has not been fully investigated.

objectivesThis study aimed to describe the trajectories of asthma-specific HRQOL over 15 months and examine the effect of asthma control status on HRQOL by taking socio-demographic factors into consideration.

methodsA total of 229 dyads of asthmatic children and their parents enroled in public insurance programs were recruited for assessing asthma control status and HRQOL over four time points of assessment. Asthma control status was measured using the Asthma Control and Communication Instrument, and asthma-specific HRQOL was assessed using the Patient-Reported Outcomes Measurement Information System's Pediatric Asthma Impact Scale. Latent growth models (LGMs) were applied to examine the trajectory of HRQOL and the factors contributing to the changes of HRQOL.

resultsUnconditional LGM revealed that HRQOL was improved over time. Conditional LGM suggested that accounting for asthma control and participants' socio-demographic factors, the variation in the initial level of HRQOL was significant, yet the rate of change was not. Conditional LGM also revealed that poorly controlled asthma status was associated with poor HRQOL at each time point (P's < 0.05). Lower parental education was associated with lower baseline HRQOL (P < 0.05). Hispanic children had a larger increase in HRQOL over time (P < 0.01) than non-Hispanic White children.

conclusionsVulnerable socio-demographic characteristics and poorly controlled asthma status affect HRQOL in children. This finding encourages interventions to improve asthma control status and HRQOL in minority children.

Indexed as

IncomeQuality of LifeAdolescentAdultAsthmaChildFemaleHealth SurveysHumansMaleMiddle AgedParentsRisk FactorsSurveys and Questionnairesasthma controlchildrenhealth-related quality of lifelatent growth modelspatient-reported outcomes

Identifiers

PMID27664979
PMCPMC5330944
OpenAlexW2522057509

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.