Evidence map›Paper›PMID 27664754›Full record

ArticleVascular pharmacology2016

The EP1/EP3 receptor agonist 17-pt-PGE

Anna Theiler, Viktoria Konya, Lisa Pasterk, Jovana Maric, Thomas Bärnthaler, Ilse Lanz, Wolfgang Platzer, Rufina Schuligoi, Akos Heinemann

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vascular pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. PGE2 Potentiates Orai1-Mediated Calcium Entry Contributing to Peripheral Sensitization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  2. Article
  3. The Role of PGEScientific reports · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anna TheilerInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: anna.theiler@medunigraz.at.
Viktoria KonyaInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: viktoria.konya@medunigraz.at.
Lisa PasterkInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: lisa.pasterk@medunigraz.at.
Jovana MaricInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: jovana.maric@medunigraz.at.
Thomas BärnthalerInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: thomas.baernthaler@medunigraz.at.
Ilse LanzInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: ilse.lanz@medunigraz.at.
Wolfgang PlatzerInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: wolfgang.platzer@medunigraz.at.
Rufina SchuligoiInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: rufina.schuligoi@medunigraz.at.
Akos HeinemannInstitute of Experimental and Clinical Pharmacology, Medical University of Graz, Universitaetsplatz 4, 8010 Graz, Austria. Electronic address: akos.heinemann@medunigraz.at.
Medical University of Graz · AT

Funding

Austrian Science Fund FWF P 26185Austrian Science Fund FWF W 1241
6 · The paper itself

Abstract

Endothelial dysfunction is a hallmark of inflammatory conditions. We recently demonstrated that prostaglandin (PG)E

Indexed as

AnimalsBlood PlateletsDinoprostoneDisease Models, AnimalEndothelial CellsGene Knockdown TechniquesHumansInflammationLipopolysaccharidesMaleMiceMice, Inbred BALB CNeutrophil InfiltrationPneumoniaReceptors, Prostaglandin E, EP1 SubtypeReceptors, Prostaglandin E, EP3 Subtype17-phenyltrinorprostaglandin E2DinoprostoneLipopolysaccharidesReceptors, Prostaglandin E, EP1 SubtypeReceptors, Prostaglandin E, EP3 SubtypeReceptors, Prostaglandin E, EP4 SubtypeRNA, Small Interfering17-Phenyl-trinor-prostaglandin E(2)Endothelial barrier functionEP receptorsPlatelet aggregationPulmonary inflammationVascular hyperpermeability

Identifiers

PMID27664754
PMCPMC6382064
OpenAlexW2521578335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.