Evidence map›Paper›PMID 27664405›Full record

ArticlePM & R : the journal of injury, function, and rehabilitation2017

Activity Limitation Stages Are Associated With Risk of Hospitalization Among Medicare Beneficiaries.

Ling Na, Qiang Pan, Dawei Xie, Jibby E Kurichi, Joel E Streim, Hillary R Bogner, Debra Saliba, Sean Hennessy

Abstract read
In one paragraph

Article in PM & R : the journal of injury, function, and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ling NaCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(∗).
Qiang PanCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(†).
Dawei XieCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(‡).
Jibby E KurichiCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(§).
Joel E StreimGeriatric Psychiatry Section of the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(¶).
Hillary R BognerCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA(‖).
Debra SalibaU.S. Department of Veterans Affairs, Geriatrics Research Education and Clinical Center, Los Angeles, CA; Borun Center, UCLA Department of Medicine, University of California, Los Angeles, CA; RAND, Santa Monica, CA(#).
Sean HennessyCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia; Center for Pharmacoepidemiology Research and Training, University of Pennsylvania, 803 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104-6021(∗∗). Electronic address: hennessy@upenn.edu.

Funding

Ambulatory Care Access and QualityR01HD074756 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI HENNESSY, SEAN · 2013 to 2017
$2.0M
Staging Activity LimitationR01AG040105 · NIA · UNIVERSITY OF PENNSYLVANIA · PI HENNESSY, SEAN · 2012 to 2016
$1.2M
NIA NIH HHS R01 AG040105NICHD NIH HHS R01 HD074756
6 · The paper itself

Abstract

backgroundActivity limitation stages based on activities of daily living (ADLs) and instrumental activities of daily living (IADLs) are associated with 3-year mortality in elderly Medicare beneficiaries, yet their associations with hospitalization risk in this population have not been studied.

objectiveTo examine the independent association of activity limitation stages with risk of hospitalization within a year among Medicare beneficiaries aged 65 years and older.

designCohort study.

settingCommunity.

participantsA total of 9447 community-dwelling elderly Medicare beneficiaries from the Medicare Current Beneficiary Survey for years 2005-2009.

methodsStages were derived for ADLs and IADLs separately. Associations of stages with time to first hospitalization and time to recurrent hospitalizations within a year were assessed with Cox proportional hazards models, with which we accounted for baseline sociodemographics, smoking status, comorbidities, and the year of survey entry. MAIN OUTCOMES: Time to first hospitalization and time to recurrent hospitalizations within 1 year. PRINCIPLE

findingsThe adjusted risk of first hospitalization increased with greater activity limitation stages (except stage III). The hazard ratios (95% confidence intervals) for ADL stages I-IV compared with stage 0 (no limitations) were 1.49 (1.36-1.63), 1.61 (1.44-1.80), 1.54 (1.35-1.76), and 2.06 (1.61-2.63), respectively. The pattern for IADL stages was similar. For recurrent hospitalizations, activity limitation stages were associated with the risk of the first hospitalization but not with subsequent hospitalizations.

conclusionActivity limitation stages are associated with the risk of first hospitalization in the subsequent year among elderly Medicare beneficiaries. Stages capture clinically interpretable profiles of ADL and IADL functionality and describe preserved functions and activity limitation in an aggregated measure. Stage can inform interventions to ameliorate disability and thus reduce the risk of a subsequent hospitalization in this population. LEVEL OF EVIDENCE: IV.

Indexed as

Activities of Daily LivingMobility LimitationAgedAged, 80 and overAge FactorsConfidence IntervalsCross-Sectional StudiesDatabases, FactualDisability EvaluationFemaleGeriatric AssessmentHospitalizationHospital MortalityHumansIndependent LivingMale

Identifiers

PMID27664405
PMCPMC5360539

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.