Evidence map›Paper›PMID 27663730›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2016

Genetic drivers of vulnerability and resistance in relapsed acute lymphoblastic leukemia.

Sydney X Lu, Omar Abdel-Wahab

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. WTAP-mediated mScience China. Life sciences · 2025
    Article
  2. [Childhood acute lymphoblastic leukemia withZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  3. Article
  4. Review
  5. Monitoring of RAS mutant clones in plasma of patients with RAS mutant metastatic colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sydney X LuHuman Oncology and Pathogenesis Program, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
Omar Abdel-WahabHuman Oncology and Pathogenesis Program, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065 abdelwao@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
Genetic and molecular basis for SRSF2 mutations in myelodysplasiaR01HL128239 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Omar Abdel-Wahab, Robert K Bradley · 2015 to 2026
$8.0M
Origins of BRAF-mutant hematologic malignancies and their therapeutic resistanceR01CA201247 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI ABDEL-WAHAB, OMAR, PARK, CHRISTOPHER Y · 2016 to 2020
$2.7M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016087NCI NIH HHS R01 CA201247NHLBI NIH HHS R01 HL128239
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pediatrics5'-NucleotidaseCREB-Binding ProteinDNA-Binding ProteinsDNA Copy Number VariationsDrug Resistance, NeoplasmHumansMutationNeoplasm ProteinsPolymorphism, Single NucleotidePrecursor Cell Lymphoblastic Leukemia-LymphomaProto-Oncogene Proteins p21(ras)Receptors, GlucocorticoidTumor Suppressor Protein p535'-NucleotidaseCREB-Binding ProteinCREBBP protein, humanDNA-Binding ProteinsKMT2D protein, humanKRAS protein, humanNeoplasm ProteinsNR3C1 protein, humanNT5C2 protein, humanProto-Oncogene Proteins p21(ras)Receptors, GlucocorticoidTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID27663730
PMCPMC5056046

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.