Evidence map›Paper›PMID 27663578›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2018

Just-in-Time Adaptive Interventions (JITAIs) in Mobile Health: Key Components and Design Principles for Ongoing Health Behavior Support.

Inbal Nahum-Shani, Shawna N Smith, Bonnie J Spring, Linda M Collins, Katie Witkiewitz, Ambuj Tewari, Susan A Murphy

13 registry-linked trialsAbstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 13 registered trials, which are not on this map. Cited by 1,143 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,143citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01814072 phase2 / phase3completednot on this map

Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity

TypeinterventionalSponsorNorthwestern UniversityRan2013 to 2017Enrolled562ConditionsWeight LossArms12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician, Text Messages, Recommendations to use meal replacements
NCT02997943 nacompletednot on this map

SMART Weight Loss Management

TypeinterventionalSponsorNorthwestern UniversityRan2017 to 2021Enrolled400ConditionsWeight LossArmsStep 1 Treatment: APP, Step 1 Treatment: APP + Coaching, Step 2 Treatment Strategy: Modest Step-up, Step 2 Treatment Strategy: Vigorous Step-up
NCT03255317 nacompletednot on this map

Developing a Flexible App Data Collection Tool for Substance Use Research

TypeinterventionalSponsorUniversity of MichiganRan2017 to 2018Enrolled74ConditionsSubstance UseArmsReinforcers, Notifications
NCT03740035 terminatednot on this map

Adaptation of an eHealth (Web-application) Platform for Delivery of a Sedentary Behavior Intervention Among Prostate Cancer Patients

TypeobservationalSponsorWake Forest University Health SciencesRan2018 to 2019Enrolled4ConditionsSedentary LifestyleArmseHealth for Sedentary Behavior
NCT03930524 nacompletednot on this mapstarted 2019, after this paper: background citation

An Adaptive Preventive Intervention to Optimize the Transition From Universal to Indicated Resources for College Student Alcohol Use

TypeinterventionalSponsorUniversity of MinnesotaRan2019 to 2022Enrolled891ConditionsCollege Student DrinkingArmsPersonalized Normative Feedback (PNF), Self-Monitoring (SM), Web-BASICS, Health Promotion Consultation, M-Bridge Online Health Coach
NCT03932903 narecruitingnot on this mapstarted 2025, after this paper: background citation

Using Real Time Mobile Health Approaches to Understand and Promote Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

TypeinterventionalSponsorNorthwestern UniversityRan2025 to 2027Enrolled60ConditionsAcute Lymphoblastic Leukemia, Lymphoblastic LymphomaArmsADAPTS (ADherence Assessments and Personalized Timely Support).
NCT04413500 naunknown statusnot on this mapstarted 2020, after this paper: background citation

iMedA: Improving MEDication Adherence Through Person Centered Care and Adaptive Interventions

TypeinterventionalSponsorHalmstad UniversityRan2020 to 2021Enrolled32ConditionsHypertensionArmsReminder, Educational message, Motivational messages, showing trends
NCT05692830 recruitingnot on this mapstarted 2022, after this paper: background citation

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

TypeobservationalSponsorUniversity of Illinois at Urbana-ChampaignRan2022 to 2027Enrolled240ConditionsAlcohol Drinking, Alcohol IntoxicationArmsAlcohol
NCT05912439 naunknown statusnot on this map

Smartphone Based Health Behaviour Intervention for Adolescents; Usage and Daily Attrition Rates.

TypeinterventionalSponsorUniversity of IcelandRan2017 to 2023Enrolled670ConditionsHealthy Adolescents in School-based PopulationArmsSidekickHealth
NCT07223736 narecruitingnot on this mapstarted 2026, after this paper: background citation

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness (PEARL): A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, San DiegoRan2026 to 2026Enrolled130ConditionsPelvic Floor Disorder, Loneliness, Postpartum, Mental HealthArmsGenerative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
NCT07511374 narecruitingnot on this mapstarted 2026, after this paper: background citation

Activating Metacognition in Daily Life: A Randomized Controlled Ecological Momentary Intervention to Improve Digital Self-Regulation and Well-Being

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2026 to 2026Enrolled240ConditionsBehavioral Self-monitoring and Metacognitive ReflectionArmsEcological momentary intervention
NCT07574463 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Development and Evaluation of a Just-in-Time Adaptive Digital Exercise Rehabilitation Program for Children After Congenital Heart Disease Surgery

TypeinterventionalSponsorThe Children's Hospital of Zhejiang University School of MedicineRan2026 to 2029Enrolled130ConditionsCongenital Heart Disease (CHD), Congenital Heart Disease in ChildrenArmsJITAI-Based Digital Exercise Rehabilitation Program, Standard Exercise Rehabilitation Program
NCT07746492 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Digital Real-Time Support for Stress-Induced Smoking and Unhealthy Eating Among Gender and Sexual Minorities in Dhaka

TypeinterventionalSponsorInternational Centre for Diarrhoeal Disease Research, BangladeshRan2026 to 2027Enrolled115ConditionsTobacco Use, Electronic Cigarette Use, Emotional Eating, Stress, PsychologicalArmsJust-in-Time Adaptive Support Message
3 · Its place in the literature

Who cites it

1,143 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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1,083 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Inbal Nahum-ShaniInstitute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Shawna N SmithDivision of General Medicine, Department of Internal Medicine and Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Bonnie J SpringFeinberg School of Medicine, Northwestern University, Evanston, IL, USA.
Linda M CollinsTheMethodology Center andDepartment ofHuman Development & Family Studies, Penn State, State College, PA, USA.
Katie WitkiewitzDepartment of Psychology, University of New Mexico, Albuquerque, NM, USA.
Ambuj TewariDepartment of Statistics and Department of EECS, University of Michigan, Ann Arbor, MI, USA.
Susan A MurphyDepartment of Statistics, and Institute for Social Research,University of Michigan, Ann Arbor, MI, USA.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Testing Relapse Recovery Intervention ComponentsP01CA180945 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI FIORE, MICHAEL C · 2014 to 2023
$23.0M
Pilot, Mentoring, and Professional Development CoreP50DA039838 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI LI, RUNZE · 2015 to 2019
$13.9M
Adaptive Interventions for Minimally Verbal Children with ASD in the CommunityR01HD073975 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KASARI, CONNIE L. · 2012 to 2016
$13.0M
TRAINING U54EB020404 · NIBIB · UNIVERSITY OF MEMPHIS · PI KUMAR, SANTOSH · 2014 to 2018
$11.3M
Novel Methods for Intensive Longitudinal Data in SMART Studies of Drug Abuse and HIVR01DA039901 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALMIRALL, DANIEL, NAHUM-SHANI, INBAL BILLIE · 2015 to 2024
$5.4M
Heart Steps: Adaptive mHealth intervention for physical-activity maintenanceR01HL125440 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Predrag Klasnja · 2015 to 2026
$3.8M
SMART Weight Loss ManagementR01DK108678 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NAHUM-SHANI, INBAL BILLIE, SPRING, BONNIE · 2016 to 2020
$3.5M
Opt-IN: Optimizing INtensive Lifestyle Intervention for Weight LossR01DK097364 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI COLLINS, LINDA M, SPRING, BONNIE · 2012 to 2016
$3.0M
Engineering an Online STI Prevention ProgramR01AA022931 · NIAAA · PENNSYLVANIA STATE UNIVERSITY, THE · PI RULISON, KELLY LIN · 2015 to 2019
$3.0M
Data-Based Methods for Just-In-Time Adaptive Interventions in Alcohol UseR01AA023187 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURPHY, SUSAN A · 2015 to 2019
$2.6M
The College-to-Work Transition & Alcohol Misuse: An Etiologic StudyR01AA022113 · NIAAA · CORNELL UNIVERSITY · PI BACHARACH, SAMUEL B · 2014 to 2018
$2.2M
NCI NIH HHS P01 CA180945NCI NIH HHS P30 CA060553NHLBI NIH HHS R01 HL125440NIAAA NIH HHS R01 AA022113NIAAA NIH HHS R01 AA022931NIAAA NIH HHS R01 AA023187NIAAA NIH HHS R21 AA018336NIBIB NIH HHS U54 EB020404NICHD NIH HHS R01 HD073975NIDA NIH HHS P50 DA039838NIDA NIH HHS R01 DA039901NIDDK NIH HHS R01 DK097364NIDDK NIH HHS R01 DK108678
6 · The paper itself

Abstract

Background: The just-in-time adaptive intervention (JITAI) is an intervention design aiming to provide the right type/amount of support, at the right time, by adapting to an individual's changing internal and contextual state. The availability of increasingly powerful mobile and sensing technologies underpins the use of JITAIs to support health behavior, as in such a setting an individual's state can change rapidly, unexpectedly, and in his/her natural environment. Purpose: Despite the increasing use and appeal of JITAIs, a major gap exists between the growing technological capabilities for delivering JITAIs and research on the development and evaluation of these interventions. Many JITAIs have been developed with minimal use of empirical evidence, theory, or accepted treatment guidelines. Here, we take an essential first step towards bridging this gap. Methods: Building on health behavior theories and the extant literature on JITAIs, we clarify the scientific motivation for JITAIs, define their fundamental components, and highlight design principles related to these components. Examples of JITAIs from various domains of health behavior research are used for illustration. Conclusions: As we enter a new era of technological capacity for delivering JITAIs, it is critical that researchers develop sophisticated and nuanced health behavior theories capable of guiding the construction of such interventions. Particular attention has to be given to better understanding the implications of providing timely and ecologically sound support for intervention adherence and retention.

Indexed as

Health BehaviorPatient ComplianceResearch DesignBehavioral MedicineHumansTelemedicine

Identifiers

PMID27663578
PMCPMC5364076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 7 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.