Evidence map›Paper›PMID 27663226›Full record

ArticleEuropean radiology2017

Whole-body MRI in patients with Non-bacterial Osteitis: Radiological findings and correlation with clinical data.

A P Arnoldi, C L Schlett, H Douis, L L Geyer, A M Voit, F Bleisteiner, A F Jansson, S Weckbach

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Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

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  12. Chronic Noninfectious Osteomyelitis: A Review of Imaging Findings.The Indian journal of radiology & imaging · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

A P ArnoldiInstitute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Nussbaumstrasse 20, 80336, Munich, Germany. Andreas.Arnoldi@med.uni-muenchen.de.
C L SchlettDiagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
H DouisDepartment of Radiology, University Hospital Birmingham, Birmingham, B15 2TH, United Kingdom.
L L GeyerInstitute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Nussbaumstrasse 20, 80336, Munich, Germany.
A M VoitDepartment of Rheumatology & Immunology, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.
F BleisteinerDepartment of Rheumatology & Immunology, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.
A F JanssonDepartment of Rheumatology & Immunology, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.
S WeckbachDiagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.
Ludwig-Maximilians-Universität München · DEUniversity Hospital Heidelberg · DENIHR Surgical Reconstruction and Microbiology Research Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows standardized reporting of WB-MRI. METHODS AND MATERIALS: In a prospective study, 40 patients with diagnosis of NBO underwent clinical examination and WB-MRI in which STIR- and T1- weighted images were assessed for NBO-typical lesions. Parameters of interest for RINBO were: number of radiologically active lesions (RAL), size of the patients' maximum RAL presence of extramedullary and spinal involvement. Results were tested for statistical agreement of clinical and MR-based lesion detection. RINBO was tested for correlation with clinical activity.

results62/95 clinically/radiologically active lesions were found in 30/33 patients. In 45 % of the cohort, more active lesions were detected by WB-MRI than by clinical examination. RINBO was a significant predictor for the presence of clinically active lesions.

conclusionWB-MRI is a powerful diagnostic tool for patients with NBO which can reveal asymptomatic disease activity. With RINBO a standardized evaluation approach is proposed which helps assessing radiologic disease burden and predicts clinical disease activity. KEY POINTS: • Whole body MRI is a powerful diagnostic tool for patients with non-bacterial Osteitis. • Whole body MRI can reveal asymptomatic disease activity. • The radiologic index RINBO offers a standardized evaluation approach.

Indexed as

AdolescentAdultBiomarkersChildFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOsteitisPhysical ExaminationProspective StudiesWhole Body ImagingYoung AdultBiomarkersActivity scoreCRMOMagnetic resonance imagingNon-bacterial OsteitisWhole body imaging

Identifiers

PMID27663226
OpenAlexW2522913703

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.