Evidence map›Paper›PMID 27663206›Full record

ArticlePharmaceutical biology2017

Antiobesity and antihyperglycaemic effects of Adiantum capillus-veneris extracts: in vitro and in vivo evaluations.

Violet Kasabri, Entisar K Al-Hallaq, Yasser K Bustanji, Khalid K Abdul-Razzak, Ismail F Abaza, Fatma U Afifi

Open access · hybridAbstract read
In one paragraph

Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Food science & nutrition · 2025
    Review
  3. Exploring the Anticancer Effect ofFood science & nutrition · 2025
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Effects ofPharmaceutical biology · 2019
    Article
  14. Supplementation ofMedicina (Kaunas, Lithuania) · 2019
    Article
  15. Article
  16. Anti-Obesity Effects of Medicinal and Edible Mushrooms.Molecules (Basel, Switzerland) · 2018
    Review
  17. Medicinal Properties ofIranian journal of public health · 2018
    Review
  18. Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
  19. Anti-inflammatory effect ofAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Violet Kasabria School of Pharmacy , The University of Jordan , Amman , Jordan.
Entisar K Al-Hallaqb MSD-Animal Health , Amman , Jordan.
Yasser K Bustanjia School of Pharmacy , The University of Jordan , Amman , Jordan.
Khalid K Abdul-Razzakc School of Pharmacy , Jordan University of Science and Technology , Irbid , Jordan.
Ismail F Abazaa School of Pharmacy , The University of Jordan , Amman , Jordan.
Fatma U Afifia School of Pharmacy , The University of Jordan , Amman , Jordan.
University of Jordan · JOJordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAdiantum capillus-veneris L. (Adiantaceae) hypocholesterolemic activity is therapeutically praised.

objectivesPharmacological modulation of pancreatic triacylglycerol lipase (PL) and α-amylase/α-glucosidase by A. capillus-veneris are evaluated. MATERIALS AND

methodsUsing positive controls (acarbose, orlistat, guar gum, atorvastatin, glipizide and metformin) as appropriate, crude aqueous extracts (AEs) of A. capillus-veneris aerial parts were tested via a combination of in vitro enzymatic (0.24-100 mg/mL), acute in vivo carbohydrate tolerance tests (125, 250 or 500 mg/kg body weight [b.wt]) and chronic in vivo studies (500 mg/kg b.wt) in high cholesterol diet (HCD) fed Wistar rats.

resultsLike acarbose, A. capillus-veneris as well as chlorogenic acid, with respective IC DISCUSSION AND

conclusionA. capillus-veneris, modulating pancreatic digestive enzymes, may be advocated as a combinatorial diabesity prevention/phytotherapy agent.

Indexed as

Adiantumalpha-AmylasesAnimalsAnti-Obesity AgentsBiomarkersBlood GlucoseDiet, High-FatDisease Models, AnimalDose-Response Relationship, DrugGlucose Tolerance TestGlycoside Hydrolase InhibitorsHypoglycemic AgentsLipaseObesityPancreasPhytotherapyalpha-AmylasesAnti-Obesity AgentsBiomarkersBlood GlucoseGlycoside Hydrolase InhibitorsHypoglycemic AgentsLipasePlant ExtractsTriglyceridesAdiantaceaehigh cholesterol dietpancreatic lipase and amylasephenolics

Identifiers

PMID27663206
PMCPMC7011982
OpenAlexW2434617889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.