ReviewCurrent neurology and neuroscience reports2016
Toward a Mechanistic Understanding of Epileptic Networks.
Review in Current neurology and neuroscience reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Spatial and spectral structure of local functional connectivity of the background intracranial EEG in patients with focal epilepsy.Frontiers in network physiology · 2025Article
- Distinct Features of Interictal Activity Predict Seizure Localization and Burden in a Mouse Model of Childhood Epilepsy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Seizure onset patterns predict outcome after stereo-electroencephalography-guided laser amygdalohippocampotomy.Epilepsia · 2023Article
- Predictors of seizure outcomes in patients with diffuse low-grade glioma-related epilepsy after complete glioma removal.CNS neuroscience & therapeutics · 2023Article
- Abnormal brain functional network dynamics in sleep-related hypermotor epilepsy.CNS neuroscience & therapeutics · 2023Article
- The role of epidemic spreading in seizure dynamics and epilepsy surgery.Network neuroscience (Cambridge, Mass.) · 2023Article
- Interictal Connectivity Revealed by Granger Analysis of Stereoelectroencephalography: Association With Ictal Onset Zone, Resection, and Outcome.Neurosurgery · 2022Article
- Diffusion tractography predicts propagated high-frequency activity during epileptic spasms.Epilepsia · 2022Article
- Epidemic models characterize seizure propagation and the effects of epilepsy surgery in individualized brain networks based on MEG and invasive EEG recordings.Scientific reports · 2022Article
- Graph theoretical measures of fast ripples support the epileptic network hypothesis.Brain communications · 2022Article
- Spatiotemporal evolution of epileptic seizure based on mutual information and dynamic brain network.BMC medical informatics and decision making · 2021Article
- Clinical characteristics of low-grade tumor-related epilepsy and its predictors for surgical outcome.Annals of clinical and translational neurology · 2021Article
- Current Pharmacologic Strategies for Treatment of Intractable Epilepsy in Children.International neurourology journal · 2021Article
- Mechanism of seizure-induced retrograde amnesia.Progress in neurobiology · 2021Article
- Visualizing Oscillations in Brain Slices With Genetically Encoded Voltage Indicators.Frontiers in neuroanatomy · 2021Article
- Astroglial Glutamine Synthetase and the Pathogenesis of Mesial Temporal Lobe Epilepsy.Frontiers in neurology · 2021Review
- Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?Epilepsia · 2020Review
- Astrocytes and Glutamine Synthetase in Epileptogenesis.Journal of neuroscience research · 2019Review
- Burst suppression uncovers rapid widespread alterations in network excitability caused by an acute seizure focus.Brain : a journal of neurology · 2019Article
- Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Focal epileptic seizures have long been considered to arise from a small susceptible brain area and spread through uninvolved regions. In the past decade, the idea that focal seizures instead arise from coordinated activity across large-scale epileptic networks has become widely accepted. Understanding the network model's applicability is critical, due to its increasing influence on clinical research and surgical treatment paradigms. In this review, we examine the origins of the concept of epileptic networks as the nidus for recurring seizures. We summarize analytical and methodological elements of epileptic network studies and discuss findings from recent detailed electrophysiological investigations. Our review highlights the strengths and limitations of the epileptic network theory as a metaphor for the complex interactions that occur during seizures. We present lines of investigation that may usefully probe these interactions and thus serve to advance our understanding of the long-range effects of epileptiform activity.
Indexed as
Identifiers
27662895What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.