Observational studyAIDS (London, England)2016
Concurrency and HIV transmission network characteristics among MSM with recent HIV infection.
Observational study in AIDS (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- HIV Response Interventions that Integrate HIV Molecular Cluster and Social Network Analysis: A Systematic Review.AIDS and behavior · 2022Pooled it
- Brief Report: Predictors of Concurrent Sexual Partnerships and Association With Recent HIV Infection in a Large Population-Based Survey in Botswana.Journal of acquired immune deficiency syndromes (1999) · 2025Trial
- Article
- An individual with multiple high-risk links uncovered: an epidemiological investigation based on molecular network analysis.Frontiers in public health · 2026Article
- Phylogenetics and molecular evolution to understand and curb the HIV pandemic.Nature reviews. Microbiology · 2026Review
- HIV molecular network in Mexico City (2021-2022): Understanding transmission dynamics through the role of newly diagnosed cases.HIV medicine · 2025Article
- Analysis of HIV transmission characteristics and intervention effects in Guangxi based on molecular networks.AIDS (London, England) · 2025Article
- Factors Associated with Low/Moderate Perceived Risk for HIV Acquisition Among Gay, Bisexual, and Other Men Who Have Sex with Men Eligible to Use Pre-exposure Prophylaxis from Brazil, Mexico, and Peru.Archives of sexual behavior · 2025Article
- PKG1 promotes the HIV-induced proliferation, migration, and fibrosis of vascular smooth muscle cells of hemorrhoids.International journal of colorectal disease · 2024Article
- Molecular network characteristics and drug resistance analysis of 392 newly reported MSM HIV/AIDS cases in Chongqing, China.Frontiers in public health · 2024Article
- Article
- Predictors of HIV Molecular Cluster Membership and Implications for Partner Services.AIDS research and human retroviruses · 2023Article
- The risk of acute and early HIV (AEH) infection among MSM with different behaviour trajectories: an open cohort study in Tianjin, China, 2011-2019.BMC infectious diseases · 2023Article
- The characteristics of HIV-1 subtype B on phylogenetic dynamic and molecular transmission network in Fuyang City, China, 2011 to 2019.Frontiers in public health · 2023Article
- Exploring and Predicting the Drivers of Ongoing HIV-1 Transmission in Guangyuan, Sichuan.Infection and drug resistance · 2023Article
- Epidemiological characteristics of HIV transmission in southeastern China from 2015 to 2020 based on HIV molecular network.Frontiers in public health · 2023Article
- A New HIV-1 KMicrobiology spectrum · 2022Article
- Factors Associated With Newly HIV Infection and Transmitted Drug Resistance Among Men Who Have Sex With Men in Harbin, P.R. China.Frontiers in public health · 2022Article
- HIV-1 genetic transmission networks among people living with HIV/AIDS in Sichuan, China: a genomic and spatial epidemiological analysis.The Lancet regional health. Western Pacific · 2022Article
- Epidemiology and Molecular Transmission Characteristics of HIV in the Capital City of Anhui Province in China.Pathogens (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveSexual partner concurrency is common among MSM and may increase the probability of HIV transmission during recent (acute or early) infection. We examined the relationship between concurrency and HIV transmission network characteristics (proxies for HIV transmission) among MSM with recent HIV infection.
designObservational study integrating behavioral, clinical, and molecular epidemiology.
methodsWe inferred a partial HIV transmission network using 986 HIV-1 pol sequences obtained from HIV-infected individuals in San Diego, California (1996-2015). We further analyzed data from 285 recently HIV-infected MSM in the network who provided information on up to three sexual partners in the past 3 months, including the timing of intercourse with each partner. Concurrency was defined as sexual partners overlapping in time. Logistic and negative binomial regressions were used to investigate the link between concurrency and HIV transmission network characteristics (i.e. clustering and degree or number of connections to others in the network) among these MSM.
resultsOf recently HIV-infected MSM (n = 285), 54% reported concurrent partnerships and 54% were connected by at least one putative transmission link to others (i.e. clustered) in the network (median degree = 1.0; interquartile range: 0.0-3.0). Concurrency was positively associated with HIV transmission network clustering (adjusted odds ratio = 1.83, 95% confidence interval: 1.08, 3.10) and degree (adjusted incidence rate ratio = 1.48, 95% confidence interval: 1.02, 2.15).
conclusionOur findings provide empirical evidence consistent with the hypothesis that concurrency facilitates HIV transmission during recent infection. Interventions to mitigate the impact of concurrency on HIV transmission may help curb the HIV epidemic among MSM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.