ArticleDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]2016
Development and Validation of a Photonumeric Scale for Evaluation of Infraorbital Hollows.
Article in Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Experimental and Clinical Evaluation of Optimized Composite Collagen-Crosslinked Hyaluronic Acid Filler for Infraorbital Rejuvenation.Aesthetic plastic surgery · 2026Trial
- Improved Infraorbital Hollowing in Chinese Adults Following Hyaluronic Acid-based Filler With Lidocaine (VYC-15L) Treatment.Aesthetic surgery journal · 2026Trial
- Evaluating the Efficacy of Combined Platelet-Rich Plasma and Microneedling for Aesthetic Rejuvenation of the Periorbital Area: A Randomized, Blinded Cohort Study.Journal of cosmetic dermatology · 2025Trial
- Effectiveness of Volbella (VYC-15L) for Infraorbital Hollowing: Patient-Reported Outcomes From a Prospective, Multicenter, Single-Blind, Randomized, Controlled Study.Aesthetic surgery journal · 2023Trial
- A Prospective, Multicenter, Single-Blind, Randomized, Controlled Study of VYC-15L, a Hyaluronic Acid Filler, in Adults for Correction of Infraorbital Hollowing.Aesthetic surgery journal · 2021Trial
- Effect of Topical Fluorouracil Cream on Photodamage: Secondary Analysis of a Randomized Clinical Trial.JAMA dermatology · 2017Trial
- Transconjunctival Lower Eyelid Blepharoplasty with Orbital Fat Repositioning and Orbicularis Oculi Muscle Suspension.Aesthetic plastic surgery · 2026Article
- The PharmaResearch Under Eyelid Fine Line Severity Scale: Development and Validation of a Standardized Clinical Assessment Tool for Infraorbital Fine Wrinkles.Journal of cosmetic dermatology · 2026Article
- Noninvasive Assessment Methods for the Therapeutic Effect Following Facial Rejuvenation.Journal of cosmetic dermatology · 2025Review
- Improved Periorbital Satisfaction After Combined Mid and Upper Facial Treatment With Hyaluronic Acid Fillers and OnabotulinumtoxinA: Effectiveness and Safety Results From a Post-Marketing Study.Journal of cosmetic dermatology · 2025Article
- Quantitative Evaluation of Improvement of Tear Trough With a Non-Cross-Linked Sodium Hyaluronic Compound: A Three-Dimensional and MRI Analysis.Journal of cosmetic dermatology · 2025Article
- Optimizing Infraorbital Hollows Treatment With Hyaluronic Acid Fillers: Overview of Anatomy, Injection Techniques, and Product Considerations.Aesthetic surgery journal. Open forum · 2025Review
- Infraorbital Rejuvenation Combined with Thread-Lifting and Non-cross-linked Hyaluronic Acid Injection: A Retrospective, Case-Series Study.Aesthetic plastic surgery · 2024Article
- Multimodal Pilot Evaluation of a Hyaluronic Acid Infraorbital Filler Using Precise, Multipositional, 3-Dimensional Imaging Quantification, Patient-Reported Outcomes, and Anatomic Cadaveric Assessments.Aesthetic surgery journal. Open forum · 2024Article
- A Quantitative Three-Dimensional Tear Trough Deformity Assessment and Its Application in Orbital Septum Fat Transposition.Aesthetic plastic surgery · 2023Article
- Infraorbital Hollow Rejuvenation: Considerations, Complications, and the Contributions of Midface Volumization.Aesthetic surgery journal. Open forum · 2023Review
- Three-dimensional quantitative analysis of temporal region morphology in Chinese young adult.PeerJ · 2023Article
- Validating the Reliability and Clinical Relevance of an Infraorbital Hollow Photonumeric Scale.Aesthetic surgery journal. Open forum · 2023Article
- Creation and validation of a photonumeric scale for assessment of lip fullness.Journal of cosmetic dermatology · 2022Article
- PN-HPTJournal of cosmetic dermatology · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA validated scale is needed for objective and reproducible comparisons of infraorbital hollows (i.e., tear troughs) before and after treatment in practice and clinical studies.
objectiveTo describe the development and validation of the 5-point photonumeric Allergan Infraorbital Hollows Scale.
methodsThe scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each grade. The clinical significance of a 1-point score difference was evaluated in a review of image pairs representing varying differences in severity. Interrater and intrarater reliability was evaluated in a live-subject validation study (N = 297) completed during 2 sessions occurring 3 weeks apart.
resultsA score difference of ≥1 point was shown to reflect a clinically significant difference (mean [95% confidence interval] absolute score difference, 0.90 [0.79-1.02] for clinically different image pairs and 0.33 [0.19-0.46] for not clinically different pairs). Intrarater agreement between the 2 validation sessions was substantial (mean weighted kappa = 0.79). Interrater agreement was substantial during the second rating session (0.70, primary end point).
conclusionThe Allergan Infraorbital Hollows Scale is a validated and reliable scale for physician rating severity of hollowing in the infraorbital area.
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