Evidence map›Paper›PMID 27661745›Full record

ArticleDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]2016

Development and Validation of a Photonumeric Scale for Evaluation of Facial Fine Lines.

Jean Carruthers, Lisa Donofrio, Bhushan Hardas, Diane K Murphy, Derek Jones, Alastair Carruthers, Jonathan M Sykes, Lela Creutz, Ann Marx, Sara Dill

Abstract readValidation Study
In one paragraph

Article in Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
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  4. Safety and Clinical Efficacy of KūlarisClinical, cosmetic and investigational dermatology · 2025
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  8. Article
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  12. Development and Validation of a Composite Skin Quality Scale.Aesthetic surgery journal. Open forum · 2024
    Article
  13. Clinical Features and Biophysical Characteristics of Lips of South Asian Women.Clinical, cosmetic and investigational dermatology · 2023
    Article
  14. Article
  15. Article
  16. PN-HPTJournal of cosmetic dermatology · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jean Carruthers*Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada; †Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut; ‡Allergan plc, Irvine, California; §Division of Dermatology, University of California, Los Angeles, Los Angeles, California; ‖Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada; ¶UC Davis Medical Group, Sacramento, California; #Peloton Advantage, LLC, Parsippany, New Jersey.
Lisa Donofrio
Bhushan Hardas
Diane K Murphy
Derek Jones
Alastair Carruthers
Jonathan M Sykes
Lela Creutz
Ann Marx
Sara Dill

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA validated scale is needed for objective and reproducible comparisons of facial fine lines before and after treatment in practice and clinical studies.

objectiveTo describe the development and validation of the 5-point photonumeric Allergan Fine Lines Scale.

methodsThe Allergan Fine Lines Scale was developed to include an assessment guide, verbal descriptors, morphed images, and real subject images for each scale grade. The clinical significance of a 1-point score difference was evaluated in a review of multiple image pairs representing varying differences in severity. Interrater and intrarater reliability was evaluated in a live subject validation study (N = 289) completed during 2 sessions occurring 3 weeks apart.

resultsA score difference of ≥1 point was shown to reflect a clinically significant difference (mean [95% CI] absolute score difference, 1.06 [0.92-1.21] for clinically different image pairs and 0.50 [0.38-0.61] for not clinically different pairs). Intrarater agreement between the 2 live subject validation sessions was almost perfect (weighted kappa = 0.85). Interrater agreement was substantial during the second rating session (0.76, primary end point).

conclusionThe Allergan Fine Lines Scale is a validated and reliable scale for physician rating of severity of superficial fine lines.

Indexed as

Skin AgingCosmetic TechniquesEstheticsFaceFemaleHumansMalePhotography

Identifiers

PMID27661745
PMCPMC5671789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.