Evidence map›Paper›PMID 27661669›Full record

ArticleInflammatory bowel diseases2016

The Impact of Ostomy on Quality of Life and Functional Status of Crohn's Disease Patients.

Maisa I Abdalla, Robert S Sandler, Michael D Kappelman, Christopher F Martin, Wenli Chen, Kristen Anton, Millie D Long

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Inflammatory bowel diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Restorative versus non-restorative total proctocolectomy: Who doesn't pouch and how do they do?Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
    Article
  4. Article
  5. 'And don't say everything will be normal!': An international cross-sectional survey on the patients' unmet sexual wellbeing needs after ostomy formation.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
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  11. ASSESSMENT OF RISK FACTORS FOR SURGERY TREATMENT OF CROHN'S DISEASE: A HOSPITAL COHORT.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maisa I Abdalla*Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and †Department of Pediatrics, Division of Pediatric Gastroenterology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Robert S Sandler
Michael D Kappelman
Christopher F Martin
Wenli Chen
Kristen Anton
Millie D Long
University of North Carolina at Chapel Hill · US

Funding

PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1985 to 2026
$30.5M
Exposure to antibiotics during infancy and subsequent risk of Crohn's disease: aK08DK088957 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAPPELMAN, MICHAEL D · 2011 to 2013
$457k
NIDDK NIH HHS K08 DK088957NIDDK NIH HHS P30 DK034987
6 · The paper itself

Abstract

backgroundThe potential need for an ostomy is a main concern for patients with inflammatory bowel disease. We performed this study to evaluate the impact of a long-term ostomy (≥6 mo duration) on the functional status and specific patient-reported outcomes in a population of patients with Crohn's disease (CD).

methodsWe performed a cross-sectional analysis within the Crohn's and Colitis Foundation of America Partners cohort. Bivariate analyses and logistic regression models were used to investigate associations between ostomy and various demographic, disease factors, and patient-reported outcomes for health-related quality of life.

resultsA total of 402 CD patients with ostomy for a minimum duration of 6 months were compared with 4331 CD patients with no ostomy. Patients with ostomy were more likely to be in clinical remission compared with those without ostomy, 48.5% versus 31.3%, respectively. Having an ostomy did not impact the overall health-related quality of life and was not associated with anxiety, depression, sleep disturbances, or reduced sexual interest and satisfaction. However, the presence of ostomy was associated with reduced social role satisfaction in both patients with controlled and active disease. Additionally, in the subset of patients who did not achieve clinical remission, those with ostomy experienced greater pain interference (odds ratio, 1.63; 95% confidence interval, 1.12-2.35) and fatigue (odds ratio, 1.66; 95% confidence interval, 1.15-2.39).

conclusionsOstomy is well tolerated in CD patients, particularly when clinical remission is achieved.

Indexed as

Patient Reported Outcome MeasuresAdultColostomyCrohn DiseaseCross-Sectional StudiesDisability EvaluationFemaleFollow-Up StudiesHumansLogistic ModelsMaleMiddle AgedPatient SatisfactionPostoperative PeriodQuality of LifeSeverity of Illness Index

Identifiers

PMID27661669
PMCPMC5087602
OpenAlexW2522135533

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.