Evidence map›Paper›PMID 27661609›Full record

ArticleMolecular pharmaceutics2016

Synthesis and Biological Activity of Highly Cationic Dendrimer Antibiotics.

Harrison W VanKoten, Wendy M Dlakic, Robert Engel, Mary J Cloninger

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Harrison W VanKotenDepartment of Chemistry and Biochemistry, Montana State University , 103 Chemistry and Biochemistry Building, Bozeman, Montana 59717, United States.
Wendy M DlakicDepartment of Chemistry and Biochemistry, Montana State University , 103 Chemistry and Biochemistry Building, Bozeman, Montana 59717, United States.
Robert EngelDepartment of Chemistry and Biochemistry, Queens College, City University of New York , 65-30 Kissena Boulevard, Queens, New York 11367, United States.
Mary J CloningerDepartment of Chemistry and Biochemistry, Montana State University , 103 Chemistry and Biochemistry Building, Bozeman, Montana 59717, United States.

Funding

Using Dendrimers to Design Multivalent Therapeutic AgentsR01GM062444 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI CLONINGER, MARY J · 2001 to 2015
$3.5M
NIGMS NIH HHS R01 GM062444
6 · The paper itself

Abstract

The development of pathogenic bacteria resistant to current treatments is a major issue facing the world today. Here, the synthesis and biological activity of fourth generation poly(amidoamine) dendrimers decorated with 1-hexadecyl-azoniabicylo[2.2.2]octane (C

Indexed as

Anti-Bacterial AgentsDendrimersGram-Negative BacteriaGram-Positive BacteriaMicrobial Sensitivity TestsQuaternary Ammonium CompoundsAnti-Bacterial AgentsDendrimersQuaternary Ammonium Compoundsantibioticcationicdendrimersmultivalencyquaternary ammonium compound

Identifiers

PMID27661609
PMCPMC9389851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.