Evidence map›Paper›PMID 27661254›Full record

ArticleeLife2016

Boundary cells restrict dystroglycan trafficking to control basement membrane sliding during tissue remodeling.

Shelly Th McClatchey, Zheng Wang, Lara M Linden, Eric L Hastie, Lin Wang, Wanqing Shen, Alan Chen, Qiuyi Chi, David R Sherwood

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Basement Membranes in Development and Disease.Current topics in developmental biology · 2018
    Review
  10. Review
  11. Breaking down barriers: the evolution of cell invasion.Current opinion in genetics & development · 2017
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Shelly Th McClatcheyDepartment of Biology, Duke University, Durham, United States.
Zheng WangCenter for Tissue Engineering and Regenerative Medicine, Union Hospital, Wuhan, China.
Lara M LindenDepartment of Biology, Duke University, Durham, United States.
Eric L HastieDepartment of Biology, Duke University, Durham, United States.
Lin WangCenter for Tissue Engineering and Regenerative Medicine, Union Hospital, Wuhan, China.
Wanqing ShenCenter for Tissue Engineering and Regenerative Medicine, Union Hospital, Wuhan, China.
Alan ChenDepartment of Biology, Duke University, Durham, United States.
Qiuyi ChiDepartment of Biology, Duke University, Durham, United States.
David R SherwoodDepartment of Biology, Duke University, Durham, United States.ORCID 0000-0003-2245-2334
Duke University · USUnion Hospital · CN

Funding

Training Program in Developmental & Stem Cell BiologyT32HD040372 · NICHD · DUKE UNIVERSITY · PI Terry H Lechler · 2001 to 2026
$8.9M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Understanding how cells invade through basement membrane in vivoR35GM118049 · NIGMS · DUKE UNIVERSITY · PI David R Sherwood · 2016 to 2026
$6.8M
Genetic Analysis of Cell Invasion through Basement MembranesR01GM079320 · NIGMS · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2007 to 2015
$2.8M
Understanding How Invadosomes Breach Basement Membrane In VivoR01GM100083 · NIGMS · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2012 to 2015
$1.1M
NICHD NIH HHS T32 HD040372NIGMS NIH HHS R01 GM079320NIGMS NIH HHS R01 GM100083NIGMS NIH HHS R35 GM118049NIH HHS P40 OD010440
6 · The paper itself

Abstract

Epithelial cells and their underlying basement membranes (BMs) slide along each other to renew epithelia, shape organs, and enlarge BM openings. How BM sliding is controlled, however, is poorly understood. Using genetic and live cell imaging approaches during uterine-vulval attachment in

Indexed as

AnimalsBasement MembraneCaenorhabditis elegansCaenorhabditis elegans ProteinsDystroglycansEpithelial CellsMovementCaenorhabditis elegans ProteinsDystroglycansbasement membraneC. eleganscell biologydystroglycanmembrane transportmorphogenesisNotch signalingSec14 family phospholipid transfer protein

Identifiers

PMID27661254
PMCPMC5061546
OpenAlexW2521821074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.