Trial reportPediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association2016
Does Exercise Decrease Pain via Conditioned Pain Modulation in Adolescents?
Trial report in Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating Specific and Non-Specific Mechanisms in Two Distinct Complementary/Integrative Interventions for Chronic Pain
Movement as Medicine: Can a Single Bout of Aerobic Exercise Elicit Exercise-induced Hypoalgesia in Youth With and Without Chronic Pain Syndromes?
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- The effect of exercise on cervical radiculopathy: A systematic review and meta-analysis.Medicine · 2019Pooled it
- Impact of repeated exposure to CPM on CPM efficiency and pain sensitivity in healthy adults: a randomized controlled trial.Frontiers in pain research (Lausanne, Switzerland) · 2025Trial
- The Effect of Praying on Endogenous Pain Modulation and Pain Intensity in Healthy Religious Individuals in Lebanon: A Randomized Controlled Trial.Journal of religion and health · 2023Trial
- Evaluation of rehabilitation effect of five-step exercises on patients with radiculopathy of cervical vertebra.Medicine · 2020Trial
- Impact of electrical muscle stimulation-induced muscle contractions on endogenous pain modulatory system: a quantitative sensory testing evaluation.BMC musculoskeletal disorders · 2024Article
- Opposite effects of isometric exercise on pain sensitivity of healthy individuals: the role of pain modulation.Pain reports · 2024Article
- How can the pain sensitivity to be affected by maximal progressive exercise test during pregnancy?PloS one · 2024Article
- Perceived Pain in Athletes: A Comparison between Endurance Runners and Powerlifters through a Cold Experimental Stimulation and Two Sessions of Various Physical Activation.Sports (Basel, Switzerland) · 2022Article
- Baduanjin exercise for cervical spondylotic radiculopathy: A protocol for systematic review and meta-analysis.Medicine · 2020Article
- The effectiveness of exercise on cervical radiculopathy: A protocol for systematic review and meta-analysis.Medicine · 2019Article
- Fatiguing Trunk Flexor Exercise Decreases Pain Sensitivity in Postpartum Women.Frontiers in physiology · 2019Article
- Systemic Exercise-Induced Hypoalgesia Following Isometric Exercise Reduces Conditioned Pain Modulation.Pain medicine (Malden, Mass.) · 2019Article
- Swimming Practice and Scapular Kinematics, Scapulothoracic Muscle Activity, and the Pressure-Pain Threshold in Young Swimmers.Journal of athletic training · 2018Article
- Brief submaximal isometric exercise improves cold pressor pain tolerance.Journal of behavioral medicine · 2017Article
- Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena.The Journal of physiology · 2017Review
- Current methodological approaches in conditioned pain modulation assessment in pediatrics.Journal of pain research · 2017Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purposePain relief after exercise, exercise-induced hypoalgesia (EIH), is established across the lifespan. Conditioned pain modulation (CPM: pain inhibits pain) may be a mechanism for EIH.
methodsIn 55 adolescents, pressure pain thresholds were measured before and after exercise (deltoid, quadriceps, and nail bed) and during CPM at the nail bed and deltoid test stimulus sites. The relationship between EIH and CPM was explored.
resultsEIH occurred at deltoid and quadriceps; CPM occurred at nail bed and deltoid. CPM and EIH correlated at deltoid; adolescents with greater CPM experienced greater pain relief after exercise. At this site, CPM predicted 5.4% of EIH. Arm lean mass did not add a significant effect. Peak exercise pain did not influence EIH. Adolescents with none, minimal, moderate, or severe peak exercise pain experienced similar EIH.
conclusionsA potential relationship exists between CPM and EIH in adolescents. Pediatric physical therapists should consider the CPM response when prescribing exercise as a pain management tool.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.