ArticlePLoS genetics2016
Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes.
Article in PLoS genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Heterokairic Genes and the Eco-Evo-Devo of Timing.Evolution & development · 2026Review
- Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Gene expression evolution is predicted by stronger indirect selection at more pleiotropic genes.Evolution letters · 2025Article
- The Evolution of Gene Expression Plasticity During Adaptation to Salt in Chlamydomonas reinhardtii.Genome biology and evolution · 2024Article
- Evolutionary adaptations generally reverse phenotypic plasticity to restore ancestral phenotypes during new environment adaptation in cattle.Ecology and evolution · 2024Article
- Evolution of Phenotypic Variance Provides Insights into the Genetic Basis of Adaptation.Genome biology and evolution · 2024Article
- Gene expression plasticity followed by genetic change during colonization in a high-elevation environment.eLife · 2024Article
- Misalignment of plastic and evolutionary responses of lifespan to novel carbohydrate diets.Royal Society open science · 2024Article
- Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness ineLife · 2023Article
- Sexual conflict, heterochrony and tissue specificity as evolutionary problems of adaptive plasticity in development.Proceedings. Biological sciences · 2023Review
- Transcriptomic analysis reveals the rareness of genetic assimilation of gene expression in environmental adaptations.Science advances · 2023Article
- Parallel adaptation to lower altitudes is associated with enhanced plasticity in Heliosperma pusillum (Caryophyllaceae).The Plant journal : for cell and molecular biology · 2023Article
- Experimental evolution of metabolism under nutrient restriction: enhanced amino acid catabolism and a key role of branched-chain amino acids.Evolution letters · 2023Article
- How predictable is adaptation from standing genetic variation? Experimental evolution inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Weak gene-gene interaction facilitates the evolution of gene expression plasticity.BMC biology · 2023Article
- Genetic assimilation of ancestral plasticity during parallel adaptation to zinc contamination in Silene uniflora.Nature ecology & evolution · 2023Article
- Experimental evolution of environmental tolerance, acclimation, and physiological plasticity in a randomly fluctuating environment.Evolution letters · 2022Article
- Distinct signals of clinal and seasonal allele frequency change at eQTLs in Drosophila melanogaster.Evolution; international journal of organic evolution · 2022Article
- Evolved Transcriptional Responses and Their Trade-Offs after Long-Term Adaptation of Bemisia tabaci to a Marginally Suitable Host.Genome biology and evolution · 2022Article
- Using phenotypic plasticity to understand the structure and evolution of the genotype-phenotype map.Genetica · 2022Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little is known of how gene expression and its plasticity evolves as populations adapt to different environmental regimes. Expression is expected to evolve adaptively in all populations but only those populations experiencing environmental heterogeneity are expected to show adaptive evolution of plasticity. We measured the transcriptome in a cadmium-enriched diet and a salt-enriched diet for experimental populations of Drosophila melanogaster that evolved for ~130 generations in one of four selective regimes: two constant regimes maintained in either cadmium or salt diets and two heterogeneous regimes that varied either temporally or spatially between the two diets. For populations evolving in constant regimes, we find a strong signature of counter-gradient evolution; the evolved expression differences between populations adapted to alternative diets is opposite to the plastic response of the ancestral population that is naïve to both diets. Based on expression patterns in the ancestral populations, we identify a set of genes for which we predict selection in heterogeneous regimes to result in increases in plasticity and we find the expected pattern. In contrast, a set of genes where we predicted reduced plasticity did not follow expectation. Nonetheless, both gene sets showed a pattern consistent with adaptive expression evolution in heterogeneous regimes, highlighting the difference between observing "optimal" plasticity and improvements in environment-specific expression. Looking across all genes, there is evidence in all regimes of differences in biased allele expression across environments ("allelic plasticity") and this is more common among genes with plasticity in total expression.
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Registered trials
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