ArticleACS biomaterials science & engineering2016
Transport of Nitric Oxide (NO) in Various Biomedical grade Polyurethanes: Measurements and Modeling Impact on NO Release Properties of Medical Devices.
Article in ACS biomaterials science & engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Slippery bioactive nanoemulsion-infused and nitric oxide-releasing surfaces for anti-fouling biomedical applications.Biomaterials science · 2026Article
- Slippery lubricant-infused surfaces with anti-fouling and antimicrobial properties for preventing biofouling in biomedical applications.Biomaterials science · 2026Review
- Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Smart and Biodegradable Polymers in Tissue Engineering and Interventional Devices: A Brief Review.Polymers · 2025Review
- Multifunctional slippery nanoemulsion-infused porous nitric oxide-releasing surfaces.Journal of colloid and interface science · 2025Article
- Enhanced antibacterial efficacy against antibiotic-resistant bacteria via nitric oxide-releasing ampicillin polymer substrates.Journal of colloid and interface science · 2024Article
- Electrochemical Generation of Nitric Oxide for Medical Applications.Electrochemical science advances · 2022Article
- Smartphone compatible nitric oxide releasing insert to prevent catheter-associated infections.Journal of controlled release : official journal of the Controlled Release Society · 2022Article
- Article
- Biobased polyurethanes for biomedical applications.Bioactive materials · 2021Review
- A Microfluidic Chip Architecture Enabling a Hypoxic Microenvironment and Nitric Oxide Delivery in Cell Culture.Micromachines · 2020Article
- Nitric Oxide-Releasing Insert for Disinfecting the Hub Region of Tunnel Dialysis Catheters.ACS applied materials & interfaces · 2020Article
- Studies of combined NO-eluting/CD47-modified polyurethane surfaces for synergistic enhancement of biocompatibility.Colloids and surfaces. B, Biointerfaces · 2020Article
- Article
- Synthesis and Characterization of a FluorinatedJournal of materials chemistry. B · 2018Article
- Antimicrobial nitric oxide releasing surfaces based on S-nitroso-N-acetylpenicillamine impregnated polymers combined with submicron-textured surface topography.Biomaterials science · 2017Article
- Physalins V-IX, 16,24-cyclo-13,14-seco withanolides from Physalis angulata and their antiproliferative and anti-inflammatory activities.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Nitric oxide (NO) releasing polymers are promising in improving the biocompatibility of medical devices. Polyurethanes are commonly used to prepare/fabricate many devices (e.g., catheters); however, the transport properties of NO within different polyurethanes are less studied, creating a gap in the rational design of new NO releasing devices involving polyurethane materials. Herein, we study the diffusion and partitioning of NO in different biomedical polyurethanes via the time-lag method. The diffusion of NO is positively correlated with the PDMS content within the polyurethanes, which can be rationalized by effective media theory considering various microphase morphologies. Using catheters as a model device, the effect of these transport properties on the NO release profiles and the distribution around an asymmetric dual lumen catheter are simulated using finite element analysis and validated experimentally. This method can be readily applied in studying other NO release medical devices with different configurations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.