Evidence map›Paper›PMID 27660804›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2016

Automatic pericardium segmentation and quantification of epicardial fat from computed tomography angiography.

Alexander Norlén, Jennifer Alvén, David Molnar, Olof Enqvist, Rauni Rossi Norrlund, John Brandberg, Göran Bergström, Fredrik Kahl

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Machine Learning Approaches in Cardiovascular Imaging.Circulation. Cardiovascular imaging · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander NorlénChalmers University of Technology , Department of Signals and Systems, Hörsalsvägen 9-11, Gothenburg 412 96, Sweden.
Jennifer AlvénChalmers University of Technology , Department of Signals and Systems, Hörsalsvägen 9-11, Gothenburg 412 96, Sweden.
David MolnarGothenburg University , Sahlgrenska Academy, Institute of Medicine, The Wallenberg Laboratory, Bruna stråket 16, Gothenburg 413 45, Sweden.
Olof EnqvistGothenburg University , Sahlgrenska Academy, Institute of Medicine, The Wallenberg Laboratory, Bruna stråket 16, Gothenburg 413 45, Sweden.
Rauni Rossi NorrlundGothenburg University , Sahlgrenska Academy, Institute of Medicine, The Wallenberg Laboratory, Bruna stråket 16, Gothenburg 413 45, Sweden.
John BrandbergGothenburg University , Sahlgrenska Academy, Institute of Medicine, The Wallenberg Laboratory, Bruna stråket 16, Gothenburg 413 45, Sweden.
Göran BergströmGothenburg University , Sahlgrenska Academy, Institute of Medicine, The Wallenberg Laboratory, Bruna stråket 16, Gothenburg 413 45, Sweden.
Fredrik KahlChalmers University of Technology, Department of Signals and Systems, Hörsalsvägen 9-11, Gothenburg 412 96, Sweden; Lund University, Faculty of Engineering, Centre for Mathematical Sciences, Sölvegatan 18, Lund 221 00, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent findings indicate a strong correlation between the risk of future heart disease and the volume of adipose tissue inside of the pericardium. So far, large-scale studies have been hindered by the fact that manual delineation of the pericardium is extremely time-consuming and that existing methods for automatic delineation lack accuracy. An efficient and fully automatic approach to pericardium segmentation and epicardial fat volume (EFV) estimation is presented, based on a variant of multi-atlas segmentation for spatial initialization and a random forest classifier for accurate pericardium detection. Experimental validation on a set of 30 manually delineated computer tomography angiography volumes shows a significant improvement on state-of-the-art in terms of EFV estimation [mean absolute EFV difference: 3.8 ml (4.7%), Pearson correlation: 0.99] with run times suitable for large-scale studies (52 s). Further, the results compare favorably with interobserver variability measured on 10 volumes.

Indexed as

computed tomography angiographyepicardial fat quantificationmachine learningpericardiumsegmentation

Identifiers

PMID27660804
PMCPMC5023657

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.