Evidence map›Paper›PMID 27660440›Full record

ArticleInternational journal of nanomedicine

Development of paclitaxel-loaded liposomal nanocarrier stabilized by triglyceride incorporation.

Soon-Seok Hong, Ju Yeon Choi, Jong Oh Kim, Mi-Kyung Lee, So Hee Kim, Soo-Jeong Lim

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Soon-Seok HongDepartment of Bioscience and Bioengineering, Sejong University, Seoul.
Ju Yeon ChoiCollege of Pharmacy, Yeungnam University, Gyeongsan.
Jong Oh KimCollege of Pharmacy, Yeungnam University, Gyeongsan.
Mi-Kyung LeeCollege of Pharmacy, Woosuk University, Wanju-gun, Jeollabuk-do.
So Hee KimCollege of Pharmacy and Research Institute of Pharmaceutical Science and Technology, Ajou University, Suwon, Republic of Korea.
Soo-Jeong LimDepartment of Bioscience and Bioengineering, Sejong University, Seoul.
Sejong University · KRYeungnam University · KRAjou University · KRWoosuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have highlighted the challenge of developing injectable liposomes as a paclitaxel (PTX) carrier, a challenge attributable to the limitations in liposomal stability caused by PTX loading. Poor stability of PTX-loaded liposomes is caused by PTX-triggered aggregation or fusion of liposomal membranes and is exacerbated in the presence of PEGylated lipid. In the present study, the effect of triglyceride incorporation on the stability of PTX-loaded/PEGylated liposomes was explored. Incorporation of a medium chain triglyceride Captex 300 into saturated phosphatidylcholine (PC)-based liposomes (1,2-dimyristoyl-

Indexed as

formulationliposomepaclitaxelPEGylationstabilitytriglyceride

Identifiers

PMID27660440
PMCPMC5019274
OpenAlexW2509539377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.