Evidence map›Paper›PMID 27660247›Full record

GuidelineSurgical endoscopy2016

Diagnosis and management of acute appendicitis. EAES consensus development conference 2015.

Ramon R Gorter, Hasan H Eker, Marguerite A W Gorter-Stam, Gabor S A Abis, Amish Acharya, Marjolein Ankersmit, Stavros A Antoniou, Simone Arolfo, Benjamin Babic, Luigi Boni and 21 more

2 registry-linked trialsAbstract readConsensus StatementPractice GuidelineSystematic Review
In one paragraph

Guideline in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 194 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
194citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03723642 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Investigation of Oxidative Stress - Open Appendectomy (OAE) Versus Laparoscopic Appendectomy (LAE) in Childhood and Adolescence - A Pilot Study

TypeinterventionalSponsorMedical University of GrazRan2019 to 2020Enrolled40ConditionsAppendicitis AcuteArmsInitial serum malondialdehyde level, Final serum malondialdehyde level, Initial differential white blood cell count, Final differential white blood cell count, Initial c-reactive protein serum level
NCT06762275 narecruitingnot on this mapstarted 2025, after this paper: background citation

Optimizing Management of Children Presenting With Acute Abdominal Pain in Primary Care: a Cluster Randomized Controlled Trial Evaluating the Impact of a Clinical Prediction Rule Including C-reactive Protein for Appendicitis

TypeinterventionalSponsorUniversity Medical Center GroningenRan2025 to 2029Enrolled566ConditionsAppendicitis Acute, Acute Abdomen in ChildrenArmsDiagnostic strategy
3 · Its place in the literature

Who cites it

194 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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  8. Rapid MRI Abdomen for Assessment of Clinically Suspected Acute Appendicitis in the General Adult Population: a Systematic Review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023
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  12. Acute Appendicitis in Childhood and Adulthood.Deutsches Arzteblatt international · 2020
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  17. Is it necessary to use specimen retrieval bag for reducing surgical site infection in laparoscopic appendectomy?A randomized controlled trial.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
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134 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Ramon R GorterDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands. rr.gorter@vumc.nl.
Hasan H EkerDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands.
Marguerite A W Gorter-StamDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands.
Gabor S A AbisDepartment of Surgery, Spaarne Gasthuis, Haarlem, The Netherlands.
Amish AcharyaDepartment of Surgery, St Mary's Hospital, London, UK.
Marjolein AnkersmitDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands.
Stavros A AntoniouDepartment of Surgery, Center for Minimally Invasive Surgery, Neuwerk Hospital, Mönchengladbach, Germany.
Simone ArolfoDepartment of Surgery, University of Torino, Torino, Italy.
Benjamin BabicDepartment of Surgery, Agaplesion Markus Krankenhaus, Frankfurt am Main, Germany.
Luigi BoniDepartment of Surgery, Minimally Invasive Surgery Research Center, University of Insubria, Varese, Italy.
Marlieke BruntinkDepartment of Surgery, Red Cross Hospital, Beverwijk, The Netherlands.
Dieuwertje A van DamDepartment of Surgery, Red Cross Hospital, Beverwijk, The Netherlands.
Barbara DefoortDepartment of Surgery, Maria Middelares Ghent, Ghent, Belgium.
Charlotte L DeijenDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands.
F Borja DeLacyDepartment of Surgery, Hospital Clinic of Barcelona, Barcelona, Spain.
Peter Mnyh GoDepartment of Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.
Annelieke M K HarmsenDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands.
Rick S van den HelderDepartment of Surgery, Noordwest Clinics Alkmaar, Alkmaar, The Netherlands.
Florin IordacheDepartment of Surgery, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
Johannes C F KetMedical Library, Vrije Universiteit, Amsterdam, The Netherlands.
Filip E MuysomsDepartment of Surgery, Maria Middelares Ghent, Ghent, Belgium.
M Mahir OzmenDepartment of Surgery, School of Medicine, Bahcesehir University, Istanbul, Turkey.
Michail PapoulasDepartment of Surgery, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel.
Michael RhodesDepartment of Surgery, Stepping Hill Hospital, Stockport, UK.
Jennifer StraatmanDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands.
Mark TenhagenDepartment of Surgery, Red Cross Hospital, Beverwijk, The Netherlands.
Victor TurradoDepartment of Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Andras VereczkeiDepartment of Surgery, Medical School University of Pécs, Pecs, Hungary.
Ramon VilallongaDepartment of Surgery, University Hospital Vall Hebrón, Barcelona, Spain.
Jort D DeelderDepartment of Surgery, Noordwest Clinics Alkmaar, Alkmaar, The Netherlands.
Jaap BonjerDepartment of Surgery, VU University Medical Centre, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unequivocal international guidelines regarding the diagnosis and management of patients with acute appendicitis are lacking. The aim of the consensus meeting 2015 of the EAES was to generate a European guideline based on best available evidence and expert opinions of a panel of EAES members. After a systematic review of the literature by an international group of surgical research fellows, an expert panel with extensive clinical experience in the management of appendicitis discussed statements and recommendations. Statements and recommendations with more than 70 % agreement by the experts were selected for a web survey and the consensus meeting of the EAES in Bucharest in June 2015. EAES members and attendees at the EAES meeting in Bucharest could vote on these statements and recommendations. In the case of more than 70 % agreement, the statement or recommendation was defined as supported by the scientific community. Results from both the web survey and the consensus meeting in Bucharest are presented as percentages. In total, 46 statements and recommendations were selected for the web survey and consensus meeting. More than 232 members and attendees voted on them. In 41 of 46 statements and recommendations, more than 70 % agreement was reached. All 46 statements and recommendations are presented in this paper. They comprise topics regarding the diagnostic work-up, treatment indications, procedural aspects and post-operative care. The consensus meeting produced 46 statements and recommendations on the diagnostic work-up and management of appendicitis. The majority of the EAES members supported these statements. These consensus proceedings provide additional guidance to surgeons and surgical residents providing care to patients with appendicitis.

Indexed as

Acute DiseaseAntibiotic ProphylaxisAppendectomyAppendicitisEuropeHumansLaparoscopyMagnetic Resonance ImagingSocieties, MedicalTime FactorsTomography, X-Ray ComputedUltrasonographyAppendectomyAppendicitisComplicated appendicitisLaparoscopic appendectomyUncomplicated appendicitis

Identifiers

PMID27660247
PMCPMC5082605

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.