Evidence map›Paper›PMID 27659943›Full record

ArticleScientific reports2016

IMNGS: A comprehensive open resource of processed 16S rRNA microbial profiles for ecology and diversity studies.

Ilias Lagkouvardos, Divya Joseph, Martin Kapfhammer, Sabahattin Giritli, Matthias Horn, Dirk Haller, Thomas Clavel

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 263 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
263citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

263 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. New microbes and new infections · 2026
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  7. Observational
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  12. Physiology, functional genomics, and proteomics ofApplied and environmental microbiology · 2026
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  13. Review
  14. Journal of microbiology and biotechnology · 2026
    Article
  15. International journal of systematic and evolutionary microbiology · 2026
    Article
  16. Article
  17. Article
  18. Article
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  20. Article

203 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilias LagkouvardosZIEL Institute for Food and Health, Core Facility NGS/Microbiome, Technische Universität München, Freising, Germany.
Divya JosephZIEL Institute for Food and Health, Core Facility NGS/Microbiome, Technische Universität München, Freising, Germany.
Martin KapfhammerZIEL Institute for Food and Health, Core Facility NGS/Microbiome, Technische Universität München, Freising, Germany.
Sabahattin GiritliZIEL Institute for Food and Health, Core Facility NGS/Microbiome, Technische Universität München, Freising, Germany.
Matthias HornDepartment of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria.
Dirk HallerZIEL Institute for Food and Health, Core Facility NGS/Microbiome, Technische Universität München, Freising, Germany.
Thomas ClavelZIEL Institute for Food and Health, Core Facility NGS/Microbiome, Technische Universität München, Freising, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SRA (Sequence Read Archive) serves as primary depository for massive amounts of Next Generation Sequencing data, and currently host over 100,000 16S rRNA gene amplicon-based microbial profiles from various host habitats and environments. This number is increasing rapidly and there is a dire need for approaches to utilize this pool of knowledge. Here we created IMNGS (Integrated Microbial Next Generation Sequencing), an innovative platform that uniformly and systematically screens for and processes all prokaryotic 16S rRNA gene amplicon datasets available in SRA and uses them to build sample-specific sequence databases and OTU-based profiles. Via a web interface, this integrative sequence resource can easily be queried by users. We show examples of how the approach allows testing the ecological importance of specific microorganisms in different hosts or ecosystems, and performing targeted diversity studies for selected taxonomic groups. The platform also offers a complete workflow for de novo analysis of users' own raw 16S rRNA gene amplicon datasets for the sake of comparison with existing data. IMNGS can be accessed at www.imngs.org.

Identifiers

PMID27659943
PMCPMC5034312

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.