Evidence map›Paper›PMID 27659730›Full record

ArticleToxicology letters2016

Differential sensitivities of bone marrow, spleen and thymus to genotoxicity induced by environmentally relevant concentrations of arsenite.

Huan Xu, Shea McClain, Sebastian Medina, Fredine T Lauer, Christelle Douillet, Ke Jian Liu, Laurie G Hudson, Miroslav Stýblo, Scott W Burchiel

Abstract read
In one paragraph

Article in Toxicology letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Risk assessment of small organoarsenic species in food.EFSA journal. European Food Safety Authority · 2024
    Article
  2. Article
  3. Update of the risk assessment of inorganic arsenic in food.EFSA journal. European Food Safety Authority · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modulation of PARP activity by Monomethylarsonous (MMAToxicology and applied pharmacology · 2021
    Article
  9. Article
  10. Observational
  11. Article
  12. Efflux Transporters Regulate Arsenite-Induced Genotoxicity in Double Negative and Double Positive T Cells.Toxicological sciences : an official journal of the Society of Toxicology · 2017
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Huan XuThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, Albuquerque, NM 87131, United States.
Shea McClainThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, Albuquerque, NM 87131, United States.
Sebastian MedinaThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, Albuquerque, NM 87131, United States.
Fredine T LauerThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, Albuquerque, NM 87131, United States.
Christelle DouilletDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.
Ke Jian LiuThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, Albuquerque, NM 87131, United States.
Laurie G HudsonThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, Albuquerque, NM 87131, United States.
Miroslav StýbloDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, United States.
Scott W BurchielThe University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, Albuquerque, NM 87131, United States. Electronic address: sburchiel@salud.unm.edu.
University of New Mexico · USUniversity of North Carolina at Chapel Hill · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
Synergistic Immunosuppression by PAHs and ArseniteR01ES019968 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BURCHIEL, SCOTT W · 2012 to 2016
$2.9M
NIDDK NIH HHS P30 DK056350NIEHS NIH HHS R01 ES019968
6 · The paper itself

Abstract

It is known in humans and mouse models, that drinking water exposures to arsenite (As

Indexed as

AnimalsArsenitesBone MarrowBone Marrow CellsComet AssayDNA DamageDose-Response Relationship, DrugDrinking WaterMaleMiceMice, Inbred C57BLMutagensOrganometallic CompoundsPoly(ADP-ribose) PolymerasesSpleenThymus GlandarseniteArsenitesDrinking Watermonomethylarsonous acidMutagensOrganometallic CompoundsPoly(ADP-ribose) PolymerasesWater Pollutants, ChemicalArsenicBone marrowGenotoxicityImmunotoxicityIntracellular arsenic speciesSpleenThymus

Identifiers

PMID27659730
PMCPMC5077650
OpenAlexW2522714512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.