ArticleInfection & chemotherapy2016
Mortality Risk Factors for Patients with Septic Shock after Implementation of the Surviving Sepsis Campaign Bundles.
Article in Infection & chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Association between incident delirium and 28- and 90-day mortality in critically ill adults: a secondary analysis.Critical care (London, England) · 2020Trial
- Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis.Yonsei medical journal · 2018Trial
- Predictors of ICU mortality in septic patients in a resource-limited African setting: a prospective multicenter cohort study in Lubumbashi, DRC.Journal of anesthesia, analgesia and critical care · 2026Article
- Association Between Lactate and ICU-Acquired Infection in Critically Ill Patients With Sepsis: A Retrospective Study Using the MIMIC-IV Database.Journal of cellular and molecular medicine · 2026Article
- Characteristics and In-Hospital Outcomes of Patients With Septic Shock in the Adult Medical Intensive Care Unit of a Tertiary Hospital in Ethiopia: A Prospective Observational Study.Health science reports · 2025Article
- Epidemiology and risk factors of fungal pathogens in sepsis: a prospective nationwide multicenter cohort study.BMC infectious diseases · 2025Article
- Determinants of Survival in obstetric Sepsis: Retrospective Observational Study.Journal of obstetrics and gynaecology of India · 2022Article
- Mortality Risk Factors for Patients With Sepsis-Induced Blood Pressure Drop: A Single-Center Retrospective Study.Cureus · 2022Article
- Clinical prediction scores and early anticoagulation therapy for new-onset atrial fibrillation in critical illness: a post-hoc analysis.BMC cardiovascular disorders · 2021Observational
- Study of thermo-regulation as a worsening marker of experimental sepsis in an animal model.Revista latino-americana de enfermagem · 2020Article
- The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single-center experience.Critical care (London, England) · 2020Observational
- The ability of an improved qSOFA score to predict acute sepsis severity and prognosis among adult patients.Medicine · 2020Observational
- Impact of body mass index on survival of medical patients with sepsis: a prospective cohort study in a university hospital in China.BMJ open · 2018Article
- Risk factors for death in septic shock: A retrospective cohort study comparing trauma and non-trauma patients.Medicine · 2017Observational
- Lactate as a Biomarker for Sepsis Prognosis?Infection & chemotherapy · 2016Article
- A Point-of-Care Serum Lactate Level and Mortality in Adult Sepsis Patients: A Community Hospital Setting.Journal of primary care & community healthArticle
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeptic shock remains a leading cause of death, despite advances in critical care management. The Surviving Sepsis Campaign (SSC) has reduced morbidity and mortality. This study evaluated risk factors for mortality in patients with septic shock who received treatment following the SSC bundles. MATERIALS AND
methodsThis retrospective cohort study included patients with septic shock who received treatments following SSC bundles in an urban emergency department between November 2007 and November 2011. Primary and secondary endpoints were all-cause 7- and 28-day mortality.
resultsAmong 436 patients, 7- and 28-day mortality rates were 7.11% (31/436) and 14% (61/436), respectively. In multivariate analysis, high lactate level (odds ratio [OR], 1.286; 95% confidence interval [CI], 1.016-1.627; P=0.036) and low estimated glomerular filtration rate (OR, 0.953; 95% CI, 0.913-0.996; P=0.032) were independent risk factors for 7-day mortality. Risk factors for 28-day mortality were high lactate level (OR, 1.346; 95% CI, 1.083-1.673; P=0.008) and high Acute Physiology and Chronic Health Evaluation II score (OR, 1.153; 95% CI, 1.029-1.293; P=0.014).
conclusionThe risk of mortality of septic shock patients remains high in patients with high lactate levels and acute kidney injury.
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