Evidence map›Paper›PMID 27659226›Full record

ArticleDiabetes2016

Exosomes in Diabetic Cardiomyopathy: The Next-Generation Therapeutic Targets?

Susmita Sahoo, Costanza Emanueli

Abstract readComment
In one paragraph

Article in Diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Emerging roles of exosomal miRNAs in diabetes mellitus.Clinical and translational medicine · 2021
    Review
  8. Extracellular vesicle interplay in cardiovascular pathophysiology.American journal of physiology. Heart and circulatory physiology · 2021
    Review
  9. Review
  10. Review
  11. Regulating microRNA expression: at the heart of diabetes mellitus and the mitochondrion.American journal of physiology. Heart and circulatory physiology · 2018
    Review
  12. Targeting miRNA for Therapy of Juvenile and Adult Diabetic Cardiomyopathy.Advances in experimental medicine and biology · 2018
    Article
  13. Article
  14. Review
  15. Article
  16. Pathological Effects of Exosomes in Mediating Diabetic Cardiomyopathy.Advances in experimental medicine and biology · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Susmita SahooCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.
Costanza EmanueliBristol Heart Institute, University of Bristol, Bristol, U.K. National Heart and Lung Institute, Imperial College London, London, U.K. costanza.emanueli@bristol.ac.uk.

Funding

Therapeutic Mechanisms of Human CD34 ExosomesR01HL124187 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SAHOO, SUSMITA · 2014 to 2018
$2.1M
British Heart Foundation RG/15/5/31446NHLBI NIH HHS R01 HL124187
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetic CardiomyopathiesExosomesCell MovementHumans

Identifiers

PMID27659226
PMCPMC5033258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.