Evidence map›Paper›PMID 27659162›Full record

ArticlePflugers Archiv : European journal of physiology2016

Cooperative roles of glucose and asparagine-linked glycosylation in T-type calcium channel expression.

Joanna Lazniewska, Yuriy Rzhepetskyy, Fang-Xiong Zhang, Gerald W Zamponi, Norbert Weiss

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Regulation of CaPflugers Archiv : European journal of physiology · 2022
    Article
  3. The life cycle of voltage-gated CaNeuronal signaling · 2021
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Genetic T-type calcium channelopathies.Journal of medical genetics · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Role of individual S4 segments in gating of CaChannels (Austin, Tex.) · 2018
    Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Joanna LazniewskaInstitute of Organic Chemistry and Biochemistry, Ion Channels and Diseases group, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Yuriy RzhepetskyyInstitute of Organic Chemistry and Biochemistry, Ion Channels and Diseases group, Academy of Sciences of the Czech Republic, Prague, Czech Republic.
Fang-Xiong ZhangDepartment of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Gerald W ZamponiDepartment of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Norbert WeissInstitute of Organic Chemistry and Biochemistry, Ion Channels and Diseases group, Academy of Sciences of the Czech Republic, Prague, Czech Republic. weiss@uochb.cas.cz.
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZUniversity of Calgary · CACzech Academy of Sciences · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-type calcium channels are key contributors to neuronal physiology where they shape electrical activity of nerve cells and contribute to the release of neurotransmitters. Enhanced T-type channel expression has been causally linked to a number of pathological conditions including peripheral painful diabetic neuropathy. Recently, it was demonstrated that asparagine-linked glycosylation not only plays an essential role in regulating cell surface expression of Ca

Indexed as

Protein Processing, Post-TranslationalAsparagineCalcium Channels, T-TypeCell MembraneGlucoseGlycosylationHEK293 CellsHumansProtein TransportAsparagineCalcium Channels, T-TypeGlucoseCalcium channelCav3.2GlucoseN-glycosylationTraffickingT-type channel

Identifiers

PMID27659162
OpenAlexW2523527814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.