ArticleJournal of medical case reports2016
Papillon-Lefèvre syndrome: a series of five cases among siblings.
Article in Journal of medical case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Clinical characteristics of Papillon-Lefèvre syndrome: A KSA perspective.Journal of Taibah University Medical Sciences · 2025Review
- Triangular Lunulae in Papillon-Lefèvre Syndrome: A Case Report.Clinical case reports · 2025Article
- Papillon-Lefèvre syndrome in dental pediatric patient: A comprehensive review.The Saudi dental journal · 2024Review
- Multidisciplinary management of Papillon-Lefevre syndrome as a result of consanguineous marriage.BMJ case reports · 2022Article
- Article
- Premature Loss of Deciduous Teeth as a Symptom of Systemic Disease: A Narrative Literature Review.International journal of environmental research and public health · 2022Review
- Case report: Corticosteroids as an adjunct treatment for the management of liver abscess in Papillon-Lefèvre syndrome: A report on two cases.Frontiers in pediatrics · 2022Article
- The first case report of Haim Munk disease with neurological manifestations and literature review.Clinical case reports · 2021Article
- Oral Phenotype and Salivary Microbiome of Individuals With Papillon-Lefèvre Syndrome.Frontiers in cellular and infection microbiology · 2021Article
- Focal palmoplantar and gingival keratosis - A rare genodermatoses: Case report.Journal of clinical and experimental dentistry · 2020Article
- Intracranial calcifications in childhood: Part 2.Pediatric radiology · 2020Review
- Papillon-Lefèvre Syndrome: Diagnosis, Dental Management, and a Case Report.Case reports in dentistry · 2019Article
- Approach to a Child with Primary Immunodeficiency Made Simple.Indian dermatology online journalReview
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPapillon-Lefèvre syndrome is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and aggressively progressing periodontitis leading to premature loss of deciduous and permanent dentition. The etiopathogenesis of the syndrome is relatively obscure, and immunologic, genetic, or possible bacterial etiologies have been proposed. CASE PRESENTATION: A series of five cases of Papillon-Lefèvre syndrome among the siblings in a family is presented here: a 3-year-old Arab girl, a 4-year-old Arab boy, a 11-year-old Arab boy, a 12-year-old Arab boy, and a 14-year-old Arab boy. The patients presented with severe gingival inflammation and mobility of teeth. The clinical manifestations were typical of Papillon-Lefèvre syndrome and the degree of involvement of the oral and skin conditions varied among them.
conclusionsThis case series stresses the consanguinity in the family as an etiologic factor. All siblings in the family were affected with Papillon-Lefèvre syndrome which makes this a rare case. A multidisciplinary approach with the active participation of a dental surgeon, dermatologist, and pediatrician is essential for the management of cases of Papillon-Lefèvre syndrome.
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