Evidence map›Paper›PMID 27658748›Full record

ArticleJournal of attention disorders2019

Fluid Reasoning Mediates the Association of Birth Weight With ADHD Symptoms in Youth From Multiplex Families With ADHD.

Julia E Morgan, Steve S Lee, Sandra K Loo

Abstract read
In one paragraph

Article in Journal of attention disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Fluid Intelligence in Children with Learning Disabilities.Psychology in Russia : state of the art · 2025
    Article
  2. COMT and DAT1 polymorphisms moderate the indirect effect of parenting behavior on youth ADHD symptoms through neurocognitive functioning.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2018
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julia E Morgan1 University of California, Los Angeles, USA.
Steve S Lee1 University of California, Los Angeles, USA.
Sandra K Loo1 University of California, Los Angeles, USA.

Funding

DETECTION OF SUSCEPTIBILITY GENES IN ADHDR01MH058277 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SMALLEY, SUSAN L · 1998 to 2008
$4.6M
Genetics of EEG Patterns in ADHDR01NS054124 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOO, SANDRA K · 2006 to 2010
$1.7M
NIMH NIH HHS R01 MH058277NINDS NIH HHS R01 NS054124
6 · The paper itself

Abstract

objectiveWe tested mediation of birth weight and ADHD symptoms by multiple biologically plausible neurocognitive functions and evaluated familiality of observed indirect effects.

method647 youth from 284 multiplex families with ADHD completed the Arithmetic, Digit Span, Vocabulary, and Block Design subtests of the Wechsler Intelligence Scale for Children (WISC). Multiple mediation tested WISC subtests as mediators of birth weight and multi-informant ADHD symptoms. Familiality of indirect effects was estimated via moderated mediation comparing conditional indirect effects across siblings concordant and discordant for ADHD.

resultsControlling for IQ and demographic factors, Arithmetic uniquely mediated birth weight and ADHD symptoms. Conditional indirect effects through Arithmetic did not differ across ADHD concordant and discordant siblings.

conclusionThese cross-sectional findings support previous prospective longitudinal research implicating Arithmetic (i.e., fluid reasoning) as a preliminary causal mediator of birth weight and ADHD symptoms, and suggest that this pathway is independent of genetic influences on ADHD.

Indexed as

Birth WeightDecision MakingMedical History TakingProblem SolvingAdolescentAttention Deficit Disorder with HyperactivityChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMental Status and Dementia TestsSiblingsWechsler ScalesYoung AdultADHDbirth weightfamilialitymultiple mediationneurocognitive functioning

Identifiers

PMID27658748
PMCPMC5360552

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.