Evidence map›Paper›PMID 27658614›Full record

ArticleeLife2016

Wnt proteins can direct planar cell polarity in vertebrate ectoderm.

Chih-Wen Chu, Sergei Y Sokol

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Linking Planar Cell Polarity to Mechanotransduction During Morphogenesis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Wnt7b acts in concert with Wnt5a to regulate tissue elongation and planar cell polarity via noncanonical Wnt signaling.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. The cellular dynamics of neural tube formation.Biochemical Society transactions · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chih-Wen ChuDepartment of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, United States.
Sergei Y SokolDepartment of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, United States.ORCID 0000-0002-3963-9202
Icahn School of Medicine at Mount Sinai · US

Funding

Novel regulators of apical constrictionR21HD078874 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SOKOL, SERGEI · 2014 to 2015
$460k
NICHD NIH HHS R21 HD078874
6 · The paper itself

Abstract

The coordinated orientation of cells across the tissue plane, known as planar cell polarity (PCP), is manifested by the segregation of core PCP proteins to different sides of the cell. Secreted Wnt ligands are involved in many PCP-dependent processes, yet whether they act as polarity cues has been controversial. We show that in

Indexed as

Cell PolarityAnimalsEctodermWnt ProteinsXenopusXenopus ProteinsWnt ProteinsXenopus Proteinscell biologydevelopmental biologygastrulationPCPPrickleskinstem cellsVangl2Wntxenopus

Identifiers

PMID27658614
PMCPMC5055393
OpenAlexW2521786941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.