Evidence map›Paper›PMID 27658506›Full record

ArticleNMR in biomedicine2016

Comparison of spoiled gradient echo and steady-state free-precession imaging for native myocardial T1 mapping using the slice-interleaved T1 mapping (STONE) sequence.

Jihye Jang, Steven Bellm, Sébastien Roujol, Tamer A Basha, Maryam Nezafat, Shingo Kato, Sebastian Weingärtner, Reza Nezafat

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in NMR in biomedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Free-breathing 3D cardiac TMagnetic resonance in medicine · 2022
    Article
  5. Review
  6. Article
  7. FASt single-breathhold 2D multislice myocardial TJournal of magnetic resonance imaging : JMRI · 2020
    Article
  8. Article
  9. Imaging sequence for joint myocardial TMagnetic resonance in medicine · 2019
    Article
  10. Article
  11. Simultaneous multislice imaging for native myocardial TMagnetic resonance in medicine · 2017
    Article
  12. Accurate myocardial T1 mapping at 5T using an improved modified Look-Locker inversion recovery method: A validation study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jihye JangDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Steven BellmDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Sébastien RoujolDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Tamer A BashaDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4431-8646
Maryam NezafatDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Shingo KatoDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Sebastian WeingärtnerDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Reza NezafatDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. rnezafat@bidmc.harvard.edu.

Funding

Cardiovascular MRI Characterization of the Arrhythmogenic Heart in Nonischemic CardiomyopathyR01HL129185 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2015 to 2024
$6.4M
An XFM Interventional Guidance System for Cardiac Resynchronization TherapyR01EB008743 · NIBIB · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2009 to 2012
$2.5M
MRI Characterization of Arrhythmogenic Scar in Ventricular TachycardiaR21HL127650 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANTER, ELAD, NEZAFAT, REZA · 2015 to 2016
$479k
NHLBI NIH HHS R01 HL129185NHLBI NIH HHS R21 HL127650NIBIB NIH HHS R01 EB008743
6 · The paper itself

Abstract

Cardiac T1 mapping allows non-invasive imaging of interstitial diffuse fibrosis. Myocardial T1 is commonly calculated by voxel-wise fitting of the images acquired using balanced steady-state free precession (SSFP) after an inversion pulse. However, SSFP imaging is sensitive to B1 and B0 imperfection, which may result in additional artifacts. A gradient echo (GRE) imaging sequence has been used for myocardial T1 mapping; however, its use has been limited to higher magnetic field to compensate for the lower signal-to-noise ratio (SNR) of GRE versus SSFP imaging. A slice-interleaved T1 mapping (STONE) sequence with SSFP readout (STONE-SSFP) has been recently proposed for native myocardial T1 mapping, which allows longer recovery of magnetization (>8 R-R) after each inversion pulse. In this study, we hypothesize that a longer recovery allows higher SNR and enables native myocardial T1 mapping using STONE with GRE imaging readout (STONE-GRE) at 1.5T. Numerical simulations and phantom and in vivo imaging were performed to compare the performance of STONE-GRE and STONE-SSFP for native myocardial T1 mapping at 1.5T. In numerical simulations, STONE-SSFP shows sensitivity to both T2 and off resonance. Despite the insensitivity of GRE imaging to T2 , STONE-GRE remains sensitive to T2 due to the dependence of the inversion pulse performance on T2 . In the phantom study, STONE-GRE had inferior accuracy and precision and similar repeatability as compared with STONE-SSFP. In in vivo studies, STONE-GRE and STONE-SSFP had similar myocardial native T1 times, precisions, repeatabilities and subjective T1 map qualities. Despite the lower SNR of the GRE imaging readout compared with SSFP, STONE-GRE provides similar native myocardial T1 measurements, precision, repeatability, and subjective image quality when compared with STONE-SSFP at 1.5T.

Indexed as

Signal Processing, Computer-AssistedAdultAlgorithmsCardiac Imaging TechniquesFemaleHeartHeart DiseasesHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedReproducibility of ResultsSensitivity and Specificitybalanced steady-state free precessioncardiovascular MR (CMR) methodsmyocardial T1 mappingrelaxometryslice-interleaved T1 mappingspoiled gradient echo

Identifiers

PMID27658506
PMCPMC5599252

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.