Evidence map›Paper›PMID 27658022›Full record

ReviewTranscription2016

Eukaryotic transcription initiation machinery visualized at molecular level.

Yan Han, Yuan He

Abstract readReview
In one paragraph

Review in Transcription, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yan Hana Department of Molecular Biosciences , Northwestern University , Evanston , IL , USA.
Yuan Hea Department of Molecular Biosciences , Northwestern University , Evanston , IL , USA.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Structure and Mechanism of Eukaryotic Transcription RegulationR01GM144559 · NIGMS · NORTHWESTERN UNIVERSITY · PI HE, YUAN · 2022 to 2025
$1.4M
NCI NIH HHS P30 CA060553NIGMS NIH HHS R01 GM144559
6 · The paper itself

Abstract

The structures of RNA Polymerase (Pol) II pre-initiation complexes (PIC) have recently been determined at near-atomic resolution, elucidating unprecedented mechanistic details of promoter opening during transcription initiation. The key structural features of promoter opening are summarized here. Structural knowledge of Pol I and III PIC is also briefly discussed.

Indexed as

AnimalsEukaryotaHumansModels, MolecularMultiprotein ComplexesPromoter Regions, GeneticRNA Polymerase IITranscription Factor TFIIHTranscription, GeneticMultiprotein ComplexesRNA Polymerase IITranscription Factor TFIIHgeneral transcription factorpre-initiation complexpromoter openingRNA polymerasetranscription initiation

Identifiers

PMID27658022
PMCPMC5066506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.