ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2016
Evaluation of Fecal Microbiota Transfer as Treatment for Postweaning Diarrhea in Research-Colony Puppies.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Fecal microbiota transplantation in puppies with canine parvovirus infection.Journal of veterinary internal medicine · 2018Trial
- Impact of fecal microbiota transplantation in dogs.Frontiers in veterinary science · 2025Article
- Clinical Guidelines for Fecal Microbiota Transplantation in Companion Animals.Advances in small animal care · 2024Article
- Evaluation of the safety and efficacy of fecal microbiota transplantations in bottlenose dolphins (Tursiops truncatus) using metagenomic sequencing.Journal of applied microbiology · 2024Article
- Microbiome Responses to Fecal Microbiota Transplantation in Cats with Chronic Digestive Issues.Veterinary sciences · 2023Article
- Machine Learning and Canine Chronic Enteropathies: A New Approach to Investigate FMT Effects.Veterinary sciences · 2022Article
- Canine Fecal Microbiota Transplantation: Current Application and Possible Mechanisms.Veterinary sciences · 2022Review
- Any Future for Faecal Microbiota Transplantation as a Novel Strategy for Gut Microbiota Modulation in Human and Veterinary Medicine?Life (Basel, Switzerland) · 2022Review
- Gut microbiota development in the growing dog: A dynamic process influenced by maternal, environmental and host factors.Frontiers in veterinary science · 2022Review
- Case Report: Oral Fecal Microbiota Transplantation in a Dog Suffering From Relapsing Chronic Diarrhea-Clinical Outcome and Follow-Up.Frontiers in veterinary science · 2022Article
- Using the canine microbiome to bridge translation of cancer immunotherapy from pre-clinical murine models to human clinical trials.Frontiers in immunology · 2022Review
- Successful outcome after a single endoscopic fecal microbiota transplantation in a Shiba dog with non-responsive enteropathy during the treatment with chlorambucil.The Journal of veterinary medical science · 2021Article
- Faecal Microbiome Transplantation as a Solution to Chronic Enteropathies in Dogs: A Case Study of Beneficial Microbial Evolution.Animals : an open access journal from MDPI · 2021Article
- Developmental stages in microbiota, bile acids, and clostridial species in healthy puppies.Journal of veterinary internal medicine · 2020Article
- Feline comorbidities: What do we really know about feline triaditis?Journal of feline medicine and surgery · 2020Review
- Proposal for rational antibacterial use in the diagnosis and treatment of dogs with chronic diarrhoea.The Journal of small animal practice · 2020Article
- The Role of the Canine Gut Microbiome and Metabolome in Health and Gastrointestinal Disease.Frontiers in veterinary science · 2019Review
- Fecal microbiota transplantation as a tool to treat and reduce susceptibility to disease in animals.Veterinary immunology and immunopathology · 2018Review
- Effect of an extruded animal protein-free diet on fecal microbiota of dogs with food-responsive enteropathy.Journal of veterinary internal medicine · 2018Article
- The Gastrointestinal Microbiome: A Review.Journal of veterinary internal medicine · 2018Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Frequently just prior to or at weaning (approximate age, 6 to 8 wk), puppies in research settings often develop diarrheal disease, which may be due, in part, to an immature and unstable intestinal microbiota that is permissive to opportunistic pathogens. The overall objective of this study was to assess whether fecal microbiota transfer (FMT) increased the transmission of a stable maternal microbiota to pups and decreased the incidence of postweaning diarrhea. Puppies were designated by litter as treated (FMT) or sham-treated. The FMT group received fecal inoculum orally for 5 consecutive days during weaning (at 6 to 8 wk of age). Diarrhea was evaluated according to a published scoring system for 11 d during the weaning period. Fresh feces were collected from dams and puppies at 3 d before weaning and 3, 10, and 24 d after weaning for analysis of the fecal microbiota by using 16S rRNA amplicon sequencing. The composition of fecal inoculum refrigerated at 3 to 5 °C was stable for at least 5 d. No diarrhea was reported in either group during the study period, making comparison of treated and control groups problematic. However, 16S rRNA gene analysis revealed microbial variability across time in both groups. Therefore, although the fecal microbiota of neither group of puppies mirrored the dam at any of the designated time points, the data provided fundamental and novel information regarding the dynamic maturation process of the fecal microbiota of puppies after weaning.
Indexed as
Identifiers
27657714PMC5029830W2531283212What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.