ArticlePloS one
Validity and Reliability of Ventilatory and Blood Lactate Thresholds in Well-Trained Cyclists.
Article in PloS one. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 6 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
83 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Immediate and short-term effect of physical exercise on BDNF in multiple sclerosis patients: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Which Training Intensity Distribution Intervention will Produce the Greatest Improvements in Maximal Oxygen Uptake and Time-Trial Performance in Endurance Athletes? A Systematic Review and Network Meta-analysis of Individual Participant Data.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Agreement Between Heart Rate Variability - Derived vs. Ventilatory and Lactate Thresholds: A Systematic Review with Meta-Analyses.Sports medicine - open · 2024Pooled it
- Heart Rate Variability-Derived Thresholds for Exercise Intensity Prescription in Endurance Sports: A Systematic Review of Interrelations and Agreement with Different Ventilatory and Blood Lactate Thresholds.Sports medicine - open · 2023Pooled it
- Factors Determining the Agreement between Aerobic Threshold and Point of Maximal Fat Oxidation: Follow-Up on a Systematic Review and Meta-Analysis on Association.International journal of environmental research and public health · 2022Pooled it
- Effects of Citrulline Supplementation on Different Aerobic Exercise Performance Outcomes: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Bypassing the systemic cardiorespiratory threshold: neuromuscular electrical stimulation elicits a SPARC response through accelerated glycolytic flux.European journal of applied physiology · 2026Trial
- Beta-alanine supplementation improves time to exhaustion, but not aerobic capacity, in competitive middle- and long-distance runners.Journal of the International Society of Sports Nutrition · 2025Trial
- Machine learning-based personalized training models for optimizing marathon performance through pyramidal and polarized training intensity distributions.Scientific reports · 2025Trial
- Correlation properties of heart rate variability for exercise prescription during prolonged running at constant speeds: A randomized cross-over trial.European journal of sport science · 2024Trial
- Use ofFrontiers in immunology · 2023Trial
- A Novel Method for Classification of Running Fatigue Using Change-Point Segmentation.Sensors (Basel, Switzerland) · 2019Trial
- Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes.Journal of the International Society of Sports Nutrition · 2018Trial
- Correlation Properties of Heart Rate Variability for Exercise Intensity Monitoring and Prescription During Constant-Load Cycling: A Comparison With Traditional Physiological Variables.European journal of sport science · 2026Article
- Lactate accumulation rate is associated with lactate turnpoints in cyclists and triathletes: a comparison of vLapeak and vLamaxEuropean journal of applied physiology · 2026Article
- Acute Physiological Responses to Different Load Components During Interval Training.Sports (Basel, Switzerland) · 2026Article
- No Detectable Effect of Caffeine Expectancy Induced by a Placebo Capsule on Time to Exhaustion at the Respiratory Compensation Point in Trained Cyclists.Sports (Basel, Switzerland) · 2026Article
- Maximal glycolytic flux modulates metabolic thresholds independent of maximal oxygen uptake.European journal of applied physiology · 2026Article
- Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut-athlete on Mars exploration missions.Experimental physiology · 2026Review
- DFAα1 as an intensity-sensitive biomarker for exercise prescription: a prospective cross-sectional study in healthy young adults.European journal of applied physiology · 2026Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to determine, i) the reliability of blood lactate and ventilatory-based thresholds, ii) the lactate threshold that corresponds with each ventilatory threshold (VT1 and VT2) and with maximal lactate steady state test (MLSS) as a proxy of cycling performance.
methodsFourteen aerobically-trained male cyclists ([Formula: see text] 62.1±4.6 ml·kg-1·min-1) performed two graded exercise tests (50 W warm-up followed by 25 W·min-1) to exhaustion. Blood lactate, [Formula: see text] and [Formula: see text] data were collected at every stage. Workloads at VT1 (rise in [Formula: see text];) and VT2 (rise in [Formula: see text]) were compared with workloads at lactate thresholds. Several continuous tests were needed to detect the MLSS workload. Agreement and differences among tests were assessed with ANOVA, ICC and Bland-Altman. Reliability of each test was evaluated using ICC, CV and Bland-Altman plots.
resultsWorkloads at lactate threshold (LT) and LT+2.0 mMol·L-1 matched the ones for VT1 and VT2, respectively (p = 0.147 and 0.539; r = 0.72 and 0.80; Bias = -13.6 and 2.8, respectively). Furthermore, workload at LT+0.5 mMol·L-1 coincided with MLSS workload (p = 0.449; r = 0.78; Bias = -4.5). Lactate threshold tests had high reliability (CV = 3.4-3.7%; r = 0.85-0.89; Bias = -2.1-3.0) except for DMAX method (CV = 10.3%; r = 0.57; Bias = 15.4). Ventilatory thresholds show high reliability (CV = 1.6%-3.5%; r = 0.90-0.96; Bias = -1.8-2.9) except for RER = 1 and V-Slope (CV = 5.0-6.4%; r = 0.79; Bias = -5.6-12.4).
conclusionsLactate threshold tests can be a valid and reliable alternative to ventilatory thresholds to identify the workloads at the transition from aerobic to anaerobic metabolism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.