Evidence map›Paper›PMID 27657355›Full record

ReviewVirulence2017

The vaginal mycobiome: A contemporary perspective on fungi in women's health and diseases.

L Latéy Bradford, Jacques Ravel

Open access · goldAbstract readReview
In one paragraph

Review in Virulence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 1 synthesis or guideline pooled it, 181 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. State-of-the-Art Review: Managing Vulvovaginal Candidiasis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
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  18. Article
  19. Article
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

L Latéy Bradforda Institute for Genome Sciences, University of Maryland School of Medicine , Baltimore , MD , USA.
Jacques Ravela Institute for Genome Sciences, University of Maryland School of Medicine , Baltimore , MD , USA.
University of Maryland, Baltimore · US

Funding

Serologic Biomarkers of Human Sexually Transmitted Infection and DiseaseU19AI084044 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KO, DENNIS CHUN-YONE · 2009 to 2018
$22.8M
EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Longitudinal Study of the Vaginal Microbiome Prior To Incident STIR01AI116799 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BROTMAN, REBECCA M. · 2015 to 2019
$3.5M
Elucidating causes of vaginal symptoms using a multi-omics approach - Admin. SupplementR01NR015495 · NINR · UNIVERSITY OF MARYLAND BALTIMORE · PI FORNEY, LARRY J, RAVEL, JACQUES · 2016 to 2020
$2.6M
NIAID NIH HHS R01 AI116799NIAID NIH HHS U19 AI084044NIGMS NIH HHS R25 GM055036NINR NIH HHS R01 NR015495
6 · The paper itself

Abstract

Most of what is known about fungi in the human vagina has come from culture-based studies and phenotypic characterization of single organisms. Though valuable, these approaches have masked the complexity of fungal communities within the vagina. The vaginal mycobiome has become an emerging field of study as genomics tools are increasingly employed and we begin to appreciate the role these fungal communities play in human health and disease. Though vastly outnumbered by its bacterial counterparts, fungi are important constituents of the vaginal ecosystem in many healthy women. Candida albicans, an opportunistic fungal pathogen, colonizes 20% of women without causing any overt symptoms, yet it is one of the leading causes of infectious vaginitis. Understanding its mechanisms of commensalism and patho-genesis are both essential to developing more effective therapies. Describing the interactions between Candida, bacteria (such as Lactobacillus spp.) and other fungi in the vagina is funda-mental to our characterization of the vaginal mycobiome.

Indexed as

MicrobiotaMycobiomeFemaleFungiHumansMicrobial InteractionsMycosesVaginaVaginitisWomen's HealthCandida albicansfungal communityfungiinfectious diseasesmicrobial ecologymicrobiomemicrobiotamycobiotavaginavulvovaginal candidiasis

Identifiers

PMID27657355
PMCPMC5411243
OpenAlexW2529888004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.