Evidence map›Paper›PMID 27657168›Full record

ArticleeLife2016

CD301b

Yosuke Kumamoto, Toshiro Hirai, Patrick W Wong, Daniel H Kaplan, Akiko Iwasaki

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. CD301bNature communications · 2025
    Article
  9. Article
  10. Classical dendritic cells contribute to hypoxia-induced pulmonary hypertension.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  11. Macro-clusters: CD301b+ DCs prime Th2 responses.The Journal of experimental medicine · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Lung IFNAR1Mucosal immunology · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yosuke KumamotoDepartment of Immunobiology, Yale University School of Medicine, New Haven, United States.
Toshiro HiraiDepartment of Dermatology, University of Pittsburgh, Pittsburgh, United States.
Patrick W WongDepartment of Immunobiology, Yale University School of Medicine, New Haven, United States.
Daniel H KaplanDepartment of Dermatology, University of Pittsburgh, Pittsburgh, United States.
Akiko IwasakiDepartment of Immunobiology, Yale University School of Medicine, New Haven, United States.ORCID http://orcid.org/0000-0002-7824-9856
Howard Hughes Medical Institute · USUniversity of Pittsburgh · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI MEGAN C KING · 1985 to 2026
$85.0M
Yale Rheumatic Diseases Research Core CenterP30AR053495 · NIAMS · YALE UNIVERSITY · PI CRAFT, JOSEPH EDGAR · 2007 to 2017
$7.0M
Immunity to Genital Herpes Simplex-2R01AI054359 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2004 to 2019
$5.2M
Antiviral CTL mobilization to the genital mucosaR01AI062428 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2005 to 2015
$3.9M
Skin Dendritic Cells and Humoral ImmunityR01AR067187 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, DANIEL H · 2015 to 2019
$1.6M
Antiviral CTL mobilization to the genital mucosaR56AI062428 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2010 to 2010
$403k
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA016359NIAID NIH HHS R01 AI054359NIAID NIH HHS R01 AI062428NIAID NIH HHS R56 AI062428NIAMS NIH HHS P30 AR053495NIAMS NIH HHS R01 AR067187
6 · The paper itself

Abstract

Strong antibody response is considered a hallmark of a successful vaccine. While dendritic cells (DCs) are important for T follicular helper (Tfh) cell priming, how this process is regulated in vivo is unclear. We show here that the depletion of CD301b

Indexed as

antibodyautoimmunitydendritic cellsgerminal centerimmunologyimmunoregulationmouseTfh

Identifiers

PMID27657168
PMCPMC5033605
OpenAlexW2521351553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.