Evidence map›Paper›PMID 27657167›Full record

ArticleeLife2016

Loss of ZBTB20 impairs circadian output and leads to unimodal behavioral rhythms.

Zhipeng Qu, Hai Zhang, Moli Huang, Guangsen Shi, Zhiwei Liu, Pancheng Xie, Hui Li, Wei Wang, Guoqiang Xu, Yang Zhang and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Zhipeng QuMOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China.
Hai ZhangDepartment of Pathophysiology, Second Military Medical University, Shanghai, China.
Moli HuangCambridge-Suda Genomic Research Center, Soochow University, Suzhou, China.
Guangsen ShiMOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China.
Zhiwei LiuCambridge-Suda Genomic Research Center, Soochow University, Suzhou, China.
Pancheng XieMOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China.ORCID http://orcid.org/0000-0001-6311-6092
Hui LiDepartment of Pathophysiology, Second Military Medical University, Shanghai, China.
Wei WangCambridge-Suda Genomic Research Center, Soochow University, Suzhou, China.
Guoqiang XuCollege of Pharmaceutical Sciences, Soochow University, Suzhou, China.
Yang ZhangCambridge-Suda Genomic Research Center, Soochow University, Suzhou, China.
Ling YangCambridge-Suda Genomic Research Center, Soochow University, Suzhou, China.
Guocun HuangDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, United States.
Joseph S TakahashiDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, United States.ORCID http://orcid.org/0000-0003-0384-8878
Weiping J ZhangDepartment of Pathophysiology, Second Military Medical University, Shanghai, China.ORCID http://orcid.org/0000-0003-4727-2380
Ying XuMOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China.ORCID http://orcid.org/0000-0002-6689-7768
Soochow University · CNModel Animal Research Center · CNSecond Military Medical University · CNThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many animals display morning and evening bimodal activities in the day/night cycle. However, little is known regarding the potential components involved in the regulation of bimodal behavioral rhythms in mammals. Here, we identified that the zinc finger protein gene

Indexed as

behavior rhythmscircadian output genelocomotormouseneurodegenerative disordersneurosciencePROKR2ZBTB20

Identifiers

PMID27657167
PMCPMC5033604
OpenAlexW2522668923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.