Evidence map›Paper›PMID 27657056›Full record

ArticleInternational journal of molecular sciences2016

Differential Impact of Hyperglycemia in Critically Ill Patients: Significance in Acute Myocardial Infarction but Not in Sepsis?

Bernhard Wernly, Michael Lichtenauer, Marcus Franz, Bjoern Kabisch, Johanna Muessig, Maryna Masyuk, Malte Kelm, Uta C Hoppe, Christian Jung

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  8. Postoperative Dynamic of Leptin and Fibroblast Growth Factor 21 in 123 Patients Recovering from Cardiac Surgery.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Article
  9. Article
  10. Hypoglycemia but Not Hyperglycemia Is Associated with Mortality in Critically Ill Patients with Diabetes.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Bernhard WernlyClinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, Salzburg A-5020, Austria. b.wernly@salk.at.
Michael LichtenauerClinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, Salzburg A-5020, Austria. m.lichtenauer@salk.at.
Marcus FranzClinic of Internal Medicine I, Department of Cardiology, Jena University Hospital, Thuringia 07743, Germany. marcus.franz@med.uni-jena.de.
Bjoern KabischClinic of Internal Medicine I, Department of Cardiology, Jena University Hospital, Thuringia 07743, Germany. bjoern.kabisch@med.uni-jena.de.
Johanna MuessigDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Düsseldorf 40225, Germany. johanna.muessig@med.uni-duesseldorf.de.
Maryna MasyukDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Düsseldorf 40225, Germany. maryna.masyuk@med.uni-duesseldorf.de.
Malte KelmDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Düsseldorf 40225, Germany. malte.kelm@med.uni-duesseldorf.de.
Uta C HoppeClinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, Salzburg A-5020, Austria. u.hoppe@salk.at.
Christian JungDivision of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Düsseldorf 40225, Germany. christian.jung@med.uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DEUniversity of Salzburg · ATJena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperglycemia is a common condition in critically ill patients admitted to an intensive care unit (ICU). These patients represent an inhomogeneous collective and hyperglycemia might need different evaluation depending on the underlying disorder. To elucidate this, we investigated and compared associations of severe hyperglycemia (>200 mg/dL) and mortality in patients admitted to an ICU for acute myocardial infarction (AMI) or sepsis as the two most frequent admission diagnoses. From 2006 to 2009, 2551 patients 69 (58-77) years; 1544 male; 337 patients suffering from type 2 diabetes (T2DM)) who were admitted because of either AMI or sepsis to an ICU in a tertiary care hospital were investigated retrospectively. Follow-up of patients was performed between May 2013 and November 2013. In a Cox regression analysis, maximum glucose concentration at the day of admission was associated with mortality in the overall cohort (HR = 1.006, 95% CI: 1.004-1.009;

Indexed as

critically illdiabeteshyperglycemiamyocardial infarctionprediabetessepsisstress hyperglycemia

Identifiers

PMID27657056
PMCPMC5037851
OpenAlexW2523015428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.