Evidence map›Paper›PMID 27656446›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

Diagnostic Pitfalls in Papillary Lesions of the Breast: Experience from a Single Tertiary Care Center.

Sridevi Hanaganahalli Basavaiah, Jessica Minal, Saraswathy Sreeram, Pooja Kundapur Suresh, Hema Kini, Deepa Adiga, Kausalya Kumari Sahu, Radha R Pai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sridevi Hanaganahalli BasavaiahAssociate Professor, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Jessica MinalAssistant Professor, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Saraswathy SreeramPostgraduate Student, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Pooja Kundapur SureshAssistant Professor, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Hema KiniProfessor, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Deepa AdigaAssociate Professor, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Kausalya Kumari SahuAdditional Professor, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Radha R PaiProfessor, Department of Pathology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Kasturba Medical College, Manipal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPapillary neoplasms are a group of lesions that are characterized by presence of papillae supported by fibrovascular cores lined by epithelial cells with or without myoepithelial cell layer. These neoplasms may be benign, atypical or malignant.

aimsThis study was conducted to analyse the clinicopathological characteristics of papillary lesions of the breast. MATERIALS AND

methodsA retrospective and prospective analysis of 34 cases of papillary lesions received over a period of 7 years from 2009 to 2015 was done. The patient's clinical details were collected from medical archives and the histopathological findings were reviewed. The lesions were classified into benign, atypical and malignant categories.

resultsDuring the study period, there were 34 cases of papillary lesions of breast. The mean age was 58 years. The central quadrant was the most common location (66.6%). The most common presenting complaint was lump (76.5% cases). Papillary lesions presented more commonly as solitary lump (82.4%) rather than multifocal disease. Benign papillary lesions were more common than the atypical and malignant lesions. The most common papillary lesion accounting for 43% of the cases was intraductal papilloma. Malignant lesions accounted for 41.2% cases with intraductal papillary carcinoma and invasive papillary carcinoma constituting 14.7% cases each.

conclusionDiagnosis of papillary carcinoma is challenging and its classification includes different entities that have specific diagnostic criteria. Due to their heterozygosity in morphology with benign, atypical and malignant subtypes, morphological features such as type of fibrovascular core and continuity of myoepithelial layer along with immunohistochemical stains for myoepithelial cells should be considered for proper and accurate diagnosis.

Indexed as

Fibrovascular coreMyoepithelialPapilloma

Identifiers

PMID27656446
PMCPMC5028439
OpenAlexW2518354499

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.