Evidence map›Paper›PMID 27656351›Full record

ArticleCurrent transplantation reports2014

Acute Antibody-Mediated Rejection in Renal Transplantation: Current Clinical Management.

Carrie Schinstock, Mark D Stegall

Open access · bronzeAbstract read
In one paragraph

Article in Current transplantation reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Safety and efficacy of eculizumab for the prevention of antibody-mediated rejection after deceased-donor kidney transplantation in patients with preformed donor-specific antibodies.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019
    Trial
  2. Review
  3. Article
  4. Characteristics of Early Antibody Mediated Rejection in Antibody Incompatible Living Donor Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Carrie SchinstockWilliam J. von Liebig Transplant Center, Mayo Clinic, Rochester, MN.
Mark D StegallWilliam J. von Liebig Transplant Center, Mayo Clinic, Rochester, MN.
Mayo Clinic in Arizona · USWinnMed · US

Funding

Intragraft expression to Predict Future GFR Decline in Kidney TransplantationU01AI096326 · NIAID · MAYO CLINIC ROCHESTER · PI STEGALL, MARK D · 2011 to 2016
$3.4M
Chronic Antibody-Mediated Injury in Renal AllograftsR01DK088791 · NIDDK · MAYO CLINIC ROCHESTER · PI STEGALL, MARK D · 2010 to 2011
$897k
Maintenance and targeting of bone marrow derived allo-reactive human plasma cellsR21AI125719 · NIAID · MAYO CLINIC ROCHESTER · PI MEDINA, KAY LYNN, STEGALL, MARK D · 2016 to 2017
$437k
NIAID NIH HHS R21 AI125719NIAID NIH HHS U01 AI096326NIDDK NIH HHS R01 DK088791
6 · The paper itself

Abstract

Acute antibody mediated rejection (AMR) is recognized as a major cause of graft loss in renal transplant recipients. Early acute AMR in the first few days after transplantation occurs primarily in sensitized renal transplant recipients with donor-specific alloantibody at the time of transplant and is a relatively "pure" form of acute AMR. Late acute AMR occurs months to years after transplantation and is commonly a mixed cellular and humoral rejection. While there is no consensus regarding optimum treatment, we contend that rational therapeutic approaches are emerging and the acute episode can be managed in most instances. However, new therapies are needed to prevent ongoing chronic injury in these patients.

Indexed as

antibody mediated rejectionkidney transplantpositive crossmatch transplantationrenal transplantationtransplant glomerulopathy

Identifiers

PMID27656351
PMCPMC5027607
OpenAlexW2018891005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.