ArticleFrontiers in plant science2016
Transcriptomics and Metabolite Analysis Reveals the Molecular Mechanism of Anthocyanin Biosynthesis Branch Pathway in Different Senecio cruentus Cultivars.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed, 64 citations in OpenAlex.
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- Integrating flavonoid metabolome and RNA-seq data unveil flower color variation in Bombax ceiba.Scientific data · 2025Article
- Genetic analysis and fine mapping reveal that AhRt3, which encodes an anthocyanin reductase, is responsible for red testa in cultivated peanuts.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Metabolome and transcriptome analysis reveal the pigments biosynthesis pathways in different color fruit peels ofFrontiers in plant science · 2024Article
- Integrated transcriptome and metabolome analysis unveils the mechanism of color-transition in Edgeworthia chrysantha tepals.BMC plant biology · 2023Article
- Comparative Transcriptome Analysis of Purple and Green Flowering Chinese Cabbage and Functional Analyses ofInternational journal of molecular sciences · 2023Article
- Expression inheritance and constraints on cis- and trans-regulatory mutations underlying lotus color variation.Plant physiology · 2023Article
- Cyanidin-3-O-glucoside Contributes to Leaf Color Change by Regulating TwoInternational journal of molecular sciences · 2023Article
- Biochemical Characterization of Black and Green Mutant Elderberry during Fruit Ripening.Plants (Basel, Switzerland) · 2023Article
- Comparative Transcriptome Analysis Unveils the Molecular Mechanism Underlying Sepal Colour Changes under Acidic pH Substratum in Hydrangea macrophyllaInternational journal of molecular sciences · 2022Article
- Transcriptomic and Metabolomic Analyses Providing Insights into the Coloring Mechanism ofFoods (Basel, Switzerland) · 2022Article
- Comparative Transcriptome Analysis of Purple and Green Non-Heading Chinese Cabbage and Function Analyses ofGenes · 2022Article
- Chemistry and Pharmacological Actions of Delphinidin, a Dietary Purple Pigment in Anthocyanidin and Anthocyanin Forms.Frontiers in nutrition · 2022Review
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- Integration of Transcriptome and Metabolome Reveals the Formation Mechanism of Red Stem inFrontiers in plant science · 2022Article
- Functional analysis of the ScAG and ScAGL11 MADS-box transcription factors for anthocyanin biosynthesis and bicolour pattern formation inHorticulture research · 2022Article
- Transcriptome analysis reveals chrysanthemum flower discoloration under high-temperature stress.Frontiers in plant science · 2022Article
- ZeMYB9 regulates cyanidin synthesis by activating the expression of flavonoid 3'-hydroxylase gene inFrontiers in plant science · 2022Article
- Transcriptomic and metabolomic joint analysis reveals distinct flavonoid biosynthesis regulation for variegated testa color development in peanut (Arachis hypogaea L.).Scientific reports · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
The cyanidin (Cy), pelargonidin (Pg), and delphinidin (Dp) pathways are the three major branching anthocyanin biosynthesis pathways that regulate flavonoid metabolic flux and are responsible for red, orange, and blue flower colors, respectively. Different species have evolved to develop multiple regulation mechanisms that form the branched pathways. In the current study, five Senecio cruentus cultivars with different colors were investigated. We found that the white and yellow cultivars do not accumulate anthocyanin and that the blue, pink, and carmine cultivars mainly accumulate Dp, Pg, and Cy in differing densities. Subsequent transcriptome analysis determined that there were 43 unigenes encoding anthocyanin biosynthesis genes in the blue cultivar. We also combined chemical and transcriptomic analyses to investigate the major metabolic pathways that are related to the observed differences in flower pigmentation in the series of S. cruentus. The results showed that mutations of the ScbHLH17 and ScCHI1/2 coding regions abolish anthocyanin formation in the white and the yellow cultivars; the competition of the ScF3'H1, ScF3'5'H, and ScDFR1/2 genes for naringenin determines the differences in branching metabolic flux of the Cy, Dp, and Pg pathways. Our findings provide new insights into the regulation of anthocyanin branching and also supplement gene resources (including ScF3'5 'H, ScF3'H, and ScDFRs) for flower color modification of ornamentals.
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