Evidence map›Paper›PMID 27656034›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2016

Hyperspectral Imaging of Neoplastic Progression in a Mouse Model of Oral Carcinogenesis.

Guolan Lu, Xulei Qin, Dongsheng Wang, Susan Muller, Hongzheng Zhang, Amy Chen, Zhuo Georgia Chen, Baowei Fei

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Adaptive deep learning for head and neck cancer detection using hyperspectral imaging.Visual computing for industry, biomedicine, and art · 2019
    Article
  10. Article
  11. Article
  12. Detection of Head and Neck Cancer in Surgical Specimens Using Quantitative Hyperspectral Imaging.Clinical cancer research : an official journal of the American Association for Cancer Research · 2017
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Guolan LuThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA.
Xulei QinDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, GA.
Dongsheng WangDepartment of Hematology and Medical Oncology, Emory University, Atlanta, GA.
Susan MullerDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA.
Hongzheng ZhangDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA.
Amy ChenDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA.
Zhuo Georgia ChenDepartment of Hematology and Medical Oncology, Emory University, Atlanta, GA.
Baowei FeiThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA; Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA; Department of Mathematics & Computer Science, Emory University, Atlanta, GA; Winship Cancer Institute of Emory University, Atlanta, GA.
Emory University · USGeorgia Institute of Technology · US

Funding

MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
Targeted fusion biopsy using anti-[18F]FACBC PET/CT and real-time 3D ultrasound gR21CA176684 · NCI · EMORY UNIVERSITY · PI FEI, BAOWEI, MASTER, VIRAJ · 2013 to 2014
$568k
NCI NIH HHS R01 CA156775NCI NIH HHS R21 CA176684
6 · The paper itself

Abstract

Hyperspectral imaging (HSI) is an emerging modality for medical applications and holds great potential for noninvasive early detection of cancer. It has been reported that early cancer detection can improve the survival and quality of life of head and neck cancer patients. In this paper, we explored the possibility of differentiating between premalignant lesions and healthy tongue tissue using hyperspectral imaging in a chemical induced oral cancer animal model. We proposed a novel classification algorithm for cancer detection using hyperspectral images. The method detected the dysplastic tissue with an average area under the curve (AUC) of 0.89. The hyperspectral imaging and classification technique may provide a new tool for oral cancer detection.

Indexed as

4NQO-induced oral cancerearly cancer detectionHyperspectral imagingimage classificationrandom forestsuperpixel

Identifiers

PMID27656034
PMCPMC5028204
OpenAlexW2332643428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.